Lactoperoxidase Antibody (15#) - BSA Free

Western Blot: Lactoperoxidase Antibody (15#) [NBP3-41574] - Sample: Lane1: Rat Salivary gland lysate; Lane2: Rat Liver lysate Primary Ab: 3ug/ml NBP3-41574; Second Ab: 0.2ug/ml HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody

Western Blot: Lactoperoxidase Antibody (15#) [NBP3-41574] - Sample: Rat Salivary Gland.

• Reactivity: Mu, Rt
• Applications: WB
• Clone: 15#
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

Lactoperoxidase Antibody (15#) - BSA Free Summary

• Immunogen: Immunized with recombinant Rat Lactoperoxidase (Uniprot#: D4A400; Pro351-Glu589 (Uniprot#: D4A400)
• Isotype: IgG2b Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: LPO
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot 0.5-5ug/ml

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH7.4, 50% glycerol
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A or G purified

Alternate Names for Lactoperoxidase Antibody (15#) - BSA Free

• EC 1.11.1
• lactoperoxidase
• MGC129990
• MGC129991
• Salivary peroxidase
• SAPX
• SPOEC 1.11.1.7

Background

Lactoperoxidase is an antibacterial agent in cow milk. The heme protein lactoperoxidase (LPO), also referred to as salivary peroxidase (SPO), is an oxidoreductase secreted into milk. LPO belongs to the XPO subfamily of the peroxidase family. It is expressed in mammary and salivary glands, and in the presence of H2O2, LPO acts as a catalyst for the oxidation of many phenols and aromatic amines. It is crucial for protecting the lactating mammary gland and intestinal tract of newborn infants against microorganisms. LPO binds one calcium ion per heterodimer and one heme B (iron-protoporphyrin IX) group covalently per heterodimer. The LPO gene, which spans 28 kb, is similar in gene organization and sequence to the peroxidase genes MPO and EPX, suggesting the possibility that these genes evolved from a common ancestral gene. The LPO and MPO genes are arranged in a tail-to-tail manner on chromosome 17q23.1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LPO