Lactoperoxidase Products

Description

Lactoperoxidase is an antibacterial agent in cow milk. The heme protein lactoperoxidase (LPO), also referred to as salivary peroxidase (SPO), is an oxidoreductase secreted into milk. LPO belongs to the XPO subfamily of the peroxidase family. It is expressed in mammary and salivary glands, and in the presence of H2O2, LPO acts as a catalyst for the oxidation of many phenols and aromatic amines. It is crucial for protecting the lactating mammary gland and intestinal tract of newborn infants against microorganisms. LPO binds one calcium ion per heterodimer and one heme B (iron-protoporphyrin IX) group covalently per heterodimer. The LPO gene, which spans 28 kb, is similar in gene organization and sequence to the peroxidase genes MPO and EPX, suggesting the possibility that these genes evolved from a common ancestral gene. The LPO and MPO genes are arranged in a tail-to-tail manner on chromosome 17q23.1.

Bioinformatics

Entrez	287610 Rat 4025 Human 76113 Mouse
Uniprot	NP_006142 Human NP_006142.1 Human P22079 Human
Product By Gene ID	4025
Alternate Names	EC 1.11.1 lactoperoxidase MGC129990 MGC129991 Salivary peroxidase SAPX SPOEC 1.11.1.7

Research Areas for Lactoperoxidase

Find related products by research area and learn more about each of the different research areas below.

Cancer
Immunology
Virology, Bacteria and Parasites