L1CAM Antibody (UJ127) [HRP]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, IHC, IHC-Fr
Clone
UJ127
Clonality
Monoclonal
Host
Mouse
Conjugate
HRP

Order Details

L1CAM Antibody (UJ127) [HRP] Summary

Immunogen
Homogenous suspension of 16 week human fetal brain
Localization
Cell surface
Marker
Axonal Marker
Specificity
Recognizes a cell surface protein of 220-240kDa, identified as L1 cell adhesion molecule. The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius); 2) MASA (mental retardation, aphasia, shuffling gait, and adducted thumbs); and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, and neural migration as well as in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm. This MAb is useful in the identification of primitive neuroectodermal tumors. It binds to tumors of neuroectodermal and glial origin e.g. neuroblastoma and Schwannomas. It does not bind to pediatric or adult brain.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
L1CAM
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
Readout System
Control
L1CAM Knockout HeLa Cell Lysate

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for L1CAM Antibody (UJ127) [HRP]

  • antigen identified by monoclonal R1
  • CAML1
  • CAML1N-CAML1
  • CD171 antigen
  • CD171
  • HSAS
  • HSAS1
  • L1 cell adhesion molecule
  • L1CAM
  • MASA
  • MIC5
  • N-CAM-L1
  • NCAM-L1
  • neural cell adhesion molecule L1
  • S10
  • SPG1

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for L1CAM Antibody (NBP2-34505H) (0)

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-34505AF350
Alexa Fluor 405 NBP2-34505AF405
Alexa Fluor 488 NBP2-34505AF488
Alexa Fluor 532 NBP2-34505AF532
Alexa Fluor 594 NBP2-34505AF594
Alexa Fluor 647 NBP2-34505AF647
Alexa Fluor 700 NBP2-34505AF700
Alexa Fluor 750 NBP2-34505AF750
Allophycocyanin NBP2-34505APC
Biotin NBP2-34505B
DyLight 350 NBP2-34505UV
DyLight 405 NBP2-34505V
DyLight 488 NBP2-34505G
DyLight 550 NBP2-34505R
DyLight 594 NBP2-34505DL594
DyLight 650 NBP2-34505C
DyLight 680 NBP2-34505FR
DyLight 755 NBP2-34505IR
FITC NBP2-34505F
HRP NBP2-34505H
Janelia Fluor 549 NBP2-34505JF549
Janelia Fluor 646 NBP2-34505JF646
PE NBP2-34505PE
PerCP NBP2-34505PCP

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Bioinformatics Tool for L1CAM Antibody (NBP2-34505H)

Discover related pathways, diseases and genes to L1CAM Antibody (NBP2-34505H). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Blogs on L1CAM.

Identifying tumoral and stromal transcriptomes that underlie tumor plasticity and stromal neuroinflammatory response in brain metastasis
By Jamshed Arslan, Pharm. D., PhD. Cancers in the brain often come from tumors elsewhere in the body. Several adaptive mechanisms influence brain metastasis, such as blood brain barrier leakage that can be induced by...  Read full blog post.

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Bioinformatics

Gene Symbol L1CAM