KLC1 Antibody [DyLight 405]

• Reactivity: Hu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: DyLight 405

KLC1 Antibody [DyLight 405] Summary

• Immunogen: The immunogen for this product maps to a region between residue 523 and 573 of human kinesin light chain 1 using the numbering given in entry NP_891553.2 (GeneID 3831).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: KLC1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for KLC1 Antibody [DyLight 405]

• hKLC1B
• hKLC1G
• hKLC1J
• hKLC1S
• kinesin 2 60/70kDa
• kinesin 2
• kinesin light chain 1
• KLC 1
• KLChKLC1N
• KNS2AhKLC1P
• KNS2hKLC1R
• medulloblastoma antigen MU-MB-2.50
• MGC15245

Background

Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named "kinesin 2", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature and/or biological validity of most of these variants have not been determined. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KLC1