Kirrel3/NEPH2 Antibody [Janelia Fluor® 549]

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Janelia Fluor 549

Kirrel3/NEPH2 Antibody [Janelia Fluor® 549] Summary

• Immunogen: Kirrel3 antibody was raised against a 19 amino acid peptide near the amino terminus of human Kirrel3. The immunogen is located within amino acids 20 - 70 of Kirrel3. Amino Acid Squence: MAKDKFRRMNEGQVYSFSQ
• Specificity: Kirrel3/NEPH2 antibody is human, mouse and rat reactive. At least two isoforms are known to exist; this antibody will detect both isoforms. Kirrel3/NEPH2 antibody is predicted to not cross-react with other members of the KIRREL protein family.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: KIRREL3
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Peptide affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Kirrel3/NEPH2 Antibody [Janelia Fluor® 549]

• KIAA1867MGC126824
• kin of IRRE like 3 (Drosophila)
• Kin of irregular chiasm-like protein 3
• kin of IRRE-like protein 3
• KIRRE
• Kirrel3
• KIRREPRO4502
• mKIRRE
• MRD4
• NEPH2
• NEPH2MGC126850
• nephrin-like 2
• Nephrin-like protein 2

Background

NEPH2 is a member of the nephrin-like protein family, which includes NEPH1 (KIRREL; MIM 607428) and NEPH3 (MIM 607762). The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2; MIM 604766), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration (Sellin et al., 2003 [PubMed 12424224]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KIRREL3