Kirrel3/NEPH2 Antibody [mFluor Violet 500 SE]

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: mFluor Violet 500 SE

Kirrel3/NEPH2 Antibody [mFluor Violet 500 SE] Summary

• Immunogen: Kirrel3 antibody was raised against a 19 amino acid peptide near the amino terminus of human Kirrel3. The immunogen is located within amino acids 20 - 70 of Kirrel3. Amino Acid Squence: MAKDKFRRMNEGQVYSFSQ
• Specificity: Kirrel3/NEPH2 antibody is human, mouse and rat reactive. At least two isoforms are known to exist; this antibody will detect both isoforms. Kirrel3/NEPH2 antibody is predicted to not cross-react with other members of the KIRREL protein family.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: KIRREL3
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Peptide affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Kirrel3/NEPH2 Antibody [mFluor Violet 500 SE]

• KIAA1867MGC126824
• kin of IRRE like 3 (Drosophila)
• Kin of irregular chiasm-like protein 3
• kin of IRRE-like protein 3
• KIRRE
• Kirrel3
• KIRREPRO4502
• mKIRRE
• MRD4
• NEPH2
• NEPH2MGC126850
• nephrin-like 2
• Nephrin-like protein 2

Background

NEPH2 is a member of the nephrin-like protein family, which includes NEPH1 (KIRREL; MIM 607428) and NEPH3 (MIM 607762). The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2; MIM 604766), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration (Sellin et al., 2003 [PubMed 12424224]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KIRREL3