KIR2DS2 Antibody Summary
Recombinant fragment corresponding to a region within amino acids 69 and 304 of KIR2DS2 (Uniprot ID#P43631)
Immunogen affinity purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
Packaging, Storage & Formulations
Store at -20C. Avoid freeze-thaw cycles.
0.1M Tris (pH 7.0), 0.1M Glycine and 20% Glycerol
Immunogen affinity purified
- Western Blot 1:500-1:3000
- Immunohistochemistry 1:10-1:500
- Immunohistochemistry-Paraffin 1:100-1:1000
suggested antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0)
Alternate Names for KIR2DS2 Antibody
- killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
- p58 KIR
- p58 NK Receptor CL-49
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
Customers Who Viewed This Item Also Viewed...
Species: Hu, Rt
Applications: WB, IHC-Fr
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P
Applications: WB, Flow, IHC-P
Applications: WB, ELISA, Flow
Applications: WB, ELISA, Flow, ICC/IF
Applications: B/N, Flow
Applications: Flow, IHC, IHC-Fr, IP
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P, IP
Applications: WB, ICC/IF, IHC, IHC-P
Applications: WB, Flow, ICC/IF, IHC-P
Species: Hu, Rt, Ze
Applications: WB, Simple Western, ELISA, Flow, ICC/IF, IHC-Fr, IHC-P, IP
Applications: Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP
Applications: Flow, Func, In vitro, In vivo, Flow-CS
Applications: Flow, Func, IHC, IHC-Fr, IHC-P, IP
Applications: WB, ICC/IF, IHC
Applications: Func, PAGE
Applications: WB, IHC, IHC-P
Publications for KIR2DS2 Antibody (NBP2-15004) (0)
There are no publications for KIR2DS2 Antibody (NBP2-15004).
By submitting your publication information earn gift cards and discounts for future purchases.
Reviews for KIR2DS2 Antibody (NBP2-15004) (0)
There are no reviews for KIR2DS2 Antibody (NBP2-15004).
By submitting a review earn points towards our Rewards Program.
- 250 points for product review
- 500 additional points for an image with your product review
- Double points (500) if you are the first to review this product
- Double points (1000) if you are the first to review this product with an image
Product General Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
FAQs for KIR2DS2 Antibody (NBP2-15004) (0)
Additional KIR2DS2 Antibody Products
Related Products by Gene
Bioinformatics Tool for KIR2DS2 Antibody (NBP2-15004)
Discover related pathways, diseases and genes to KIR2DS2 Antibody (NBP2-15004). Need help?
Read the Bioinformatics Tool Guide
for instructions on using this tool.
Blogs on KIR2DS2