Kir3.3 Antibody - BSA Free

Immunohistochemistry-Paraffin: Kir3.3 Antibody [NBP2-57515] - Staining of human pancreas shows low expression as expected.

Immunohistochemistry-Paraffin: Kir3.3 Antibody [NBP2-57515] - Staining of human cerebral cortex shows high expression.

Immunohistochemistry-Paraffin: Kir3.3 Antibody [NBP2-57515] - Staining in human cerebral cortex and pancreas tissues using anti-KCNJ9 antibody. Corresponding KCNJ9 RNA-seq data are presented for the same tissues.

• Reactivity: Hu, Mu, Rt
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Kir3.3 Antibody - BSA Free Summary

• Immunogen: This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: RLDAHLYWSIPSRLDEKVEEE
• Predicted Species: Mouse (100%), Rat (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: KCNJ9
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  Kir3.3 Recombinant Protein Antigen (NBP2-57515PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for Kir3.3 Antibody - BSA Free

• G protein-activated inward rectifier potassium channel 3
• G protein-coupled inward rectifier potassium channel
• GIRK-3
• GIRK3KIR3.3
• Inward rectifier K(+) channel Kir3.3
• inwardly rectifier K+ channel KIR3.3
• Kir3.3
• Potassium channel, inwardly rectifying subfamily J member 9
• potassium inwardly-rectifying channel, subfamily J, member 9

Background

The Kir3.3 (KCNJ9) encodes for a 393 amino acid long, 44 kDA, G-protein activated inward rectifier potassium channel protein that creates heteromultimeric pore-forming complexes. The Kir3.3 gene has been investigated in generalized epilepsy, meniere's disease, pertussis, lung cancer, schizophrenia, and diabetes mellitus. It interacts with the DRD4, KCNJ6, ADRB2, KCNJ3, and DRD2 genes in potassium transporting pathways (inward and outward), G-Beta gamma signaling, neurotransmitter receptor binding and downward transmission in the postsynaptic cell, and ion currents in synaptic transmission.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KCNJ9