KIR2.3 Products

Description

The KIR2.3 (KCNJ4) gene codes for protein that is 445 amino acid long inward rectifier potassium channel that regulates channel flow critical for electrical signaling of the nervous system, allowing for muscle excitability and neural firing. The KCNJ4 has a mass of approximately 49 kDA. Researchers are investigating the role of the KIR2.3 gene in meniere's disease, neuronitis, hyperglycemia, and noma. This gene has been shown to interact with other genes such as LIN7B, CASK, DLG4, IL16, and DLG1 in pathways such as potassium transport (in and out), antiarrhythmic pathways, dopamine-DARPP32 feedback onto cAMP pathways, and in the cholinergic synapse.

Bioinformatics

Entrez	3761 Human
Uniprot	CAK54537.1 Human NM_152868 Human NP_004972 Human P48050 Human
Product By Gene ID	3761
Alternate Names	hippocampal inward rectifier potassium channel Hippocampal inward rectifier HIRhIRK2 HIRK2 HRK1MGC142066 Inward rectifier K(+) channel Kir2.3 inward rectifier K+ channel Kir2.3 inward rectifier potassium channel 4 IRK-3 IRK3MGC142068 Kir2.3 Potassium channel, inwardly rectifying subfamily J member 4 potassium inwardly-rectifying channel, subfamily J, member 4