Kinesin 5B Antibody (KN-03) - BSA Free

Immunohistochemistry: Kinesin 5B Antibody (KN-03) [NBP3-27944] - Immunohistochemistry of human heart tissue stained using Kinesin 5B Monoclonal Antibody.

• Reactivity: Hu, Mu, Rt, Po
• Applications: ICC/IF, IHC
• Clone: KN-03
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free

Kinesin 5B Antibody (KN-03) - BSA Free Summary

• Immunogen: Enriched fraction of porcine brain Kinesin 5B.
• Specificity: Recognizes heavy chain of conventional kinesin associated with vesicles and with lower affinity with denatured molecule
• Isotype: IgM
• Clonality: Monoclonal
• Host: Mouse
• Gene: KIF5B
• Purity: Thiophilic Chromatography

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry-Paraffin 10 ug/ml

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS (pH 7.4)
• Preservative: 15mM Sodium Azide
• Purity: Thiophilic Chromatography

Alternate Names for Kinesin 5B Antibody (KN-03) - BSA Free

• Conventional kinesin heavy chain
• kinesin family member 5B
• kinesin-1 heavy chain
• KNS1kinesin 1 (110-120kD)
• KNSKINH
• Ubiquitous kinesin heavy chain
• UKHCkinesin heavy chain

Background

KIF5B is a kinesin. These are microtubule based motor proteins involved in the transport of organelles in eukaryotic cells. They typically consist of 2 identical, approximately 110 to 120 kD heavy chains and 2 identical, approximately 60 to 70 kD light chains. The heavy chain contains 3 domains: a globular N terminal motor domain, which converts the chemical energy of ATP into a motile force along microtubules in 1 fixed direction; a central alpha helical rod domain, which enables the 2 heavy chains to dimerize; and a globular C terminal domain, which interacts with light chains and possibly an organelle receptor.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KIF5B
• Uniprot:
  • P33176(Human)