Kif4A Antibody

Western Blot: Kif4A Antibody [NB100-57512] - Detection of Human KIF4A on HeLa whole cell lysate using NB100-57512. KIF4A was also immunoprecipitated by rabbit anti-KIF4A antibody NB100-57511.

• Reactivity: Hu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

Kif4A Antibody Summary

• Description: Novus Biologicals Rabbit Kif4A Antibody (NB100-57512) is a polyclonal antibody validated for use in WB and IP. Anti-Kif4A Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: The immunogen recognized by this antibody maps to a region between residue 1182 and the C-terminus (residue 1232) of human kinesin family member 4A using the numbering given in entry NP_036442.3 (GeneID 24137).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: KIF4A
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 2-5 ug/mg lysate
  • Western Blot 1:2000 to 1:10000

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: TBS and 0.1% BSA
• Preservative: 0.09% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for Kif4A Antibody

• chromokinesin-A
• chromosome-associated kinesin KIF4A
• FLJ12530
• FLJ12655
• FLJ14204
• FLJ20631
• HSA271784
• KIF4G1
• KIF4KIF4-G1
• kinesin family member 4A

Background

The kinesin superfamily of proteins consists of over forty KIF motor proteins that function in intracellular transport along microtubules. Kinesin activity has been linked to various cellular functions such as vesicle transport, mitotic spindle formation, chromosome segregation, and cytokinesis. Structurally, all kinesins contain a motor domain with microtubule and nucleotide binding sites that utilize ATP to target cargo along microtubule filaments. KIF14 silencing experiments suggest that KIF14 plays a multi-functional role in mitosis and cytokinesis. KIF4A has been shown to be essential for cytokinesis. KIF4A is also known as kinesin family member 4A, chromosome-associated kinesin KIF4A, chromokinesin, KIF4, KIF4-G1, FLJ12530, FLJ12655, FLJ14204, FLJ20631, and HSA271784.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Kif4A Antibody (NB100-57512)(1)

Publication using NB100-57512

• Shrestha S, Wilmeth LJ, Eyer J et al. PRC1 controls spindle polarization and recruitment of cytokinetic factors during monopolar cytokinesis. Mol Biol Cell 2012-04-01 [PMID: 22323288]

Bioinformatics

• Gene Symbol: KIF4A
• Entrez:
  • 24137(Human)
• Uniprot:
  • NP_036442.3(Human)