Kif4A Products

Description

The kinesin superfamily of proteins consists of over forty KIF motor proteins that function in intracellular transport along microtubules. Kinesin activity has been linked to various cellular functions such as vesicle transport, mitotic spindle formation, chromosome segregation, and cytokinesis. Structurally, all kinesins contain a motor domain with microtubule and nucleotide binding sites that utilize ATP to target cargo along microtubule filaments. KIF14 silencing experiments suggest that KIF14 plays a multi-functional role in mitosis and cytokinesis. KIF4A has been shown to be essential for cytokinesis. KIF4A is also known as kinesin family member 4A, chromosome-associated kinesin KIF4A, chromokinesin, KIF4, KIF4-G1, FLJ12530, FLJ12655, FLJ14204, FLJ20631, and HSA271784.

Bioinformatics

Entrez	24137 Human 16571 Mouse
Uniprot	AAH50548.1 Human NP_036442 Human AAH03664 Human O95239 Human
Product By Gene ID	24137
Alternate Names	Chromokinesin-A FLJ20631 chromosome-associated kinesin KIF4A FLJ14204 chromokinesin-A FLJ12655 KIF4G1 FLJ12530 KIF4KIF4-G1 HSA271784 kinesin family member 4A

Diseases related to Kif4A

Discover more about diseases related to Kif4A.

Neoplasms
Malignant Neoplasms
Uterine Cervical Neoplasm
Aneuploidy
Carcinoma
Immunologic Deficiency Syndromes
Adenocarcinoma
Cell Transformation, Neoplastic
Malignant Neoplasm Of Stomach
Basal Cell Carcinoma
Cholangiocarcinoma
Stomach Neoplasms
Malignant Tumor Of Cervix
Malignant Neoplasm Of Lung
Carcinogenesis
Malignant Neoplasm Of Pancreas
Lung Neoplasms
Non-small Cell Lung Carcinoma
Liver Carcinoma

Pathways for Kif4A

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Mitosis
Anaphase
Cytokinesis
Localization
Cell Cycle
Interphase
Chromosome Condensation
Metaphase
Transport
Cell Division
Pathogenesis
Rna Interference
Atp-dependent Chromatin Remodeling
Immune Response
Mitotic Chromosome Condensation
Neurogenesis
Chromosome Segregation
Chromatin Remodeling
Intracellular Transport
Cell Proliferation

Research Areas for Kif4A

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Core ESC-Like Genes
Lipid and Metabolism
Mitotic Regulators
Neuroscience
Stem Cell Markers

PTMs for Kif4A

Learn more about PTMs related to Kif4A.

Phosphorylation
Methylation
Dephosphorylation

Bioinformatics Tool for Kif4A

Discover related pathways, diseases and genes to Kif4A. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.