KCC4/SLC12A7 Antibody

Product Discontinued

KCC4/SLC12A7 Antibody Summary

• Immunogen: Peptide with sequence C-QLIHDRNTASHT corresponding to internal region according to NP_006589.2.
• Epitope: C-QLIHDRNTASHT
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: SLC12A7
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:2000
• Application Notes: WB: Preliminary experiments in human heart and kidney lysates gave no specific signal but low background.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for KCC4/SLC12A7 Antibody

• DKFZp434F076
• KCC4
• KCC4Electroneutral potassium-chloride cotransporter 4
• K-Cl cotransporter 4
• potassium/chloride transporter KCC4
• SLC12A7
• solute carrier family 12 (potassium/chloride transporters), member 7
• solute carrier family 12 member 7

Background

KCC4 mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inn

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for KCC4/SLC12A7 Antibody (NBP1-06045)(1)

Publication using NBP1-06045

• Simard CF, Bergeron MJ, Frenette-Cotton R et al. Homooligomeric and heterooligomeric associations between K+-Cl- cotransporter isoforms and between K+-Cl- and Na+-K+-Cl- cotransporters. J Biol Chem 2007-06-22 [PMID: 17462999]

Bioinformatics

• Gene Symbol: SLC12A7
• Entrez:
  • 10723(Human)
  • 20499(Mouse)
• Uniprot:
  • NP_006589.2(Human)