Kallikrein 1 Antibody (3G2) - Azide and BSA Free

Sandwich ELISA: Kallikrein 1 Antibody (3G2) [H00003816-M01] - Detection limit for recombinant GST tagged KLK1 is 0.3 ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: WB, ELISA, IHC
• Clone: 3G2
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

Kallikrein 1 Antibody (3G2) - Azide and BSA Free Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: KLK1 (AAH05313, 168 a.a. ~ 262 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. FPDDLQCVDLKILPNDECKKVHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIEDTIAENS
• Specificity: KLK1 - kallikrein 1, renal/pancreas/salivary
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: KLK1
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Sandwich ELISA
  • Western Blot 1:500
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control. IHC-P usage reported in scientific literature (PMID: 26231762).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Kallikrein 1 Antibody (3G2) - Azide and BSA Free

• EC 3.4.21
• EC 3.4.21.35
• glandular kallikrein 1
• hK1
• Kallikrein 1
• kallikrein 1, renal/pancreas/salivary
• kallikrein serine protease 1
• kallikrein-1
• Kidney/pancreas/salivary gland kallikrein
• KLK1
• Klk6
• KLKR
• Tissue kallikrein

Background

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Kallikrein 1 Antibody (H00003816-M01)(2)

Publications using H00003816-M01

• Drucker KL, Gianinni C, Decker PA et al. Prognostic significance of multiple kallikreins in high-grade astrocytoma. BMC Cancer. 2015-08-03 [PMID: 26231762] (IHC-P, Human)
• Halbert D, Domenyuk V, Spetzler D et al. Aptamers and uses thereof United States Patent Application US 9958448 B2 2018-01-01

Bioinformatics

• Gene Symbol: KLK1
• Entrez:
  • 3816(Human)
• OMIM:
  • 147910(Human)
• Uniprot:
  • AAH05313(Human)