KA1/GRIK4/Glutamate Receptor KA1 Antibody (1060003) [Alexa Fluor® 488]

• Reactivity: Hu
• Applications: IHC
• Clone: 1060003
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

KA1/GRIK4/Glutamate Receptor KA1 Antibody (1060003) [Alexa Fluor® 488] Summary

• Immunogen: Human KA1/GRIK containing peptide
  Accession # Q16099
• Specificity: Detects human KA1/GRIK in direct ELISA.
• Source: N/A
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for KA1/GRIK4/Glutamate Receptor KA1 Antibody (1060003) [Alexa Fluor® 488]

• EAA1
• Excitatory amino acid receptor 1
• GluK4
• glutamate receptor KA1
• Glutamate receptor KA-1
• glutamate receptor, ionotropic kainate 4
• glutamate receptor, ionotropic, kainate 4
• GRIK4
• KA1
• KA1GRIK

Background

GRIK4 (Glutamate receptor, ionotropic kainate 4) is a receptor for glutamate and is one of the 5 types of kainate receptor subunits.  Glutamate acts as an excitatory neurotransmitter at many synapses in the CNS are key mediators of brain communication.  Kainate receptors are relevant targets for neuroprotection of both neurons and glia in acute and chronic neurodegerative diseases.  They are also involved in epilepsy, pain and psychiatric disorders.  Variations in GRIK4 have been associated with both increased and decreased risk of bipolar disorder.  Single-nucleotide polymorphism's in GRIK 4 are also observed in Schizophrenia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.