Recombinant Human Intelectin-1/Omentin Protein

Recombinant Human Intelectin-1/Omentin Protein [NBP1-72371]

• Reactivity: Hu
• Applications: PAGE
• Concentration: 1 mg/ml

Recombinant Human Intelectin-1/Omentin Protein Summary

• Description: An un-tagged denatured recombinant protein corresponding to the amino acids 17-313 of Human Intelectin-1/Omentin
  
  

  Source: E.coli

  Amino Acid Sequence: MWSTDEANTY FKEWTCSSSP SLPRSCKEIK DECPSAFDGL YFLRTENGVI YQTFCDMTSG GGGWTLVASV HENDMRGKCT VGDRWSSQQG SKAVYPEGDG NWANYNTFGS AEAATSDDYK NPGYYDIQAK DLGIWHVPNK SPMQHWRNSS LLRYRTDTGF LQTLGHNLFG IYQKYPVKYG EGKCWTDNGP VIPVVYDFGD AQKTASYYSP YGQREFTAGF VQFRVFNNER AANALCAGMR VTGCNTEHHC IGGGGYFPEA SPQQCGDFSG FDWSGYGTHV GYSSSREITE AAVLLFYR

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: ITLN1
• Purity: >90%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Application Notes: Denatured protein is most likely not the best option for functional studies. It is better suited for Western Blot (WB) or imaging assays.
• Theoretical MW: 33.2 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl buffer (pH 8.0), 0.4M UREA, 10% glycerol
• Preservative: No Preservative
• Concentration: 1 mg/ml
• Purity: >90%, by SDS-PAGE

Alternate Names for Recombinant Human Intelectin-1/Omentin Protein

• Endothelial lectin HL-1
• FLJ20022
• Galactofuranose-binding lectin
• hIntL
• HL-1
• intelectin 1 (galactofuranose binding)
• Intelectin1
• Intelectin-1
• INTLHL1
• ITLN1
• Itlna
• ITLNITLN-1
• LFR
• LFRIntestinal lactoferrin receptor
• Omentin
• Omentin-1

Background

ITLN1, also known as intelectin1 or omentin, has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. ITLN1 may play a role in the defense system against microorganisms and specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Publications for Intelectin-1/Omentin Recombinant Protein (NBP1-72371)(2)

Publications using NBP1-72371

• Xiang Y, Zhou Z, Zhu L et al. Omentin-1 Enhances the Inhibitory Effect of Endothelial Progenitor Cells on Neointimal Hyperplasia by Inhibiting the P38 MAPK/CREB Pathway SSRN 2023-03-10 [PMID: 37652153] (CellProlif)
• Xiang Y, Zhou Z, Zhu L et al. Omentin-1 Enhances the Inhibition of Endothelial Progenitor Cells on Neointimal Hyperplasia via Inhibiting p38 MAPK/CREB Pathway SSRN Electronic Journal 2022-02-24

FAQs for Intelectin-1/Omentin Recombinant Protein (NBP1-72371). (Showing 1 - 2 of 2 FAQs).

1. Can you please tell me whether these proteins are active or not? Cat# P3719 Cat# NBP1-72371 Cat# P3774
   • None of these proteins are predicted to be active. They are intended to be used as a positive control in Western Blots and ELISA.
2. Can you please provide me with cDNA clone details of these proteins? Cat# P3719 Cat# NBP1-72371 Cat# P3774
   • I cannot provide you with the details of the cDNA clones used to generate these proteins, but our individual datasheets for each protein lists the length.

Bioinformatics

• Gene Symbol: ITLN1