Integrin beta 7 Antibody (2G18) - Azide and BSA Free

Immunohistochemistry: Integrin beta 7 Antibody (2G18) [NB110-94147] - LPAM-1 immunohistochemistry staining of paraffin sections of mouse spleen from LPS exposed animals.

• Reactivity: Mu
• Applications: Flow, IHC, IP
• Clone: 2G18
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: LYOPH

Integrin beta 7 Antibody (2G18) - Azide and BSA Free Summary

• Immunogen: Cell lysates of mouse lymphocytes
• Isotype: IgG2
• Clonality: Monoclonal
• Host: Rat
• Gene: ITGB7
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1:50-1:200
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:100-200
  • Immunoprecipitation 1:100-1:400

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein A or G purified
• Reconstitution Instructions: Reconstitute with sterilized PBS to a final concentration of 0.4 mg/ml.

Alternate Names for Integrin beta 7 Antibody (2G18) - Azide and BSA Free

• Gut homing receptor beta subunit
• integrin beta 7 subunit
• Integrin beta 7
• integrin beta-7
• integrin, beta 7
• ITGB7

Background

Integrin alpha 4 beta 7, also known as, the lymphocyte Peyer's patch adhesion molecule (LPAM1) is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. The alpha 4 beta 7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer's patches and intestinal lamina propria. This antibody has been shown to be useful for studies of the induction of homotypic cellular aggregation and the blockade of binding to cell adhesion molecules.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ITGB7
• Entrez:
  • 16401(Mouse)