Integrin alpha 6/CD49f Antibody (GoH3) [Phycoerythrin]

Mouse splenocytes were stained with Rat Anti-Human/Mouse/Bovine Integrin a6/CD49f PE-conjugated Monoclonal Antibody (Catalog # FAB13501P) and Rat Anti-Mouse CD3 APC-conjugated Monoclonal Antibody (Catalog # FAB4841A). Quadrant markers were set based on control antibody staining (Catalog # IC006P). View our protocol for Staining Membrane-associated Proteins.

Human peripheral blood lymphocytes were stained with Rat Anti-Human/Mouse/Bovine Integrin a6/CD49f PE-conjugated Monoclonal Antibody (Catalog # FAB13501P, filled histogram) or isotype control antibody (Catalog # IC006P, open histogram). View our protocol for Staining Membrane-associated Proteins.

• Reactivity: Hu, Mu, Bv
• Applications: Flow
• Clone: GoH3
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Phycoerythrin

Integrin alpha 6/CD49f Antibody (GoH3) [Phycoerythrin] Summary

• Additional Information: Clone GoH3 was used by HLDA to establish CD designation
• Immunogen: Mouse mammary tumor cells
• Specificity: Detects human, mouse, and bovine Integrin alpha 6/CD49f. Recognizes an epitope in the extracellular domain of the Integrin alpha 6 subunit.
• Source: N/A
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Gene: ITGA6
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 10 uL/10^6 cells

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
• Buffer: Supplied in a saline solution containing BSA and Sodium Azide.
• Preservative: Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Integrin alpha 6/CD49f Antibody (GoH3) [Phycoerythrin]

• CD49 antigen-like family member F
• CD49f antigen
• CD49f
• DKFZp686J01244
• FLJ18737
• Integrin alpha 6
• integrin alpha-6
• integrin alpha6B
• integrin, alpha 6
• ITGA6
• ITGA6B
• Platelet gpl
• VLA-6

Background

The Integrin alpha 6 subunit, also known as CD49f and VLA-6 alpha subunit, forms a heterodimer with Integrin beta 1 (CD29) or beta 4 (CD104) subunits and recognizes laminin as a ligand.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Integrin alpha 6/CD49f Antibody (FAB13501P)(5)

Publications using FAB13501P

• Li, S;Wong, A;Sun, H;Bhatia, V;Javier, G;Jana, S;Montgomery, RB;Wright, JL;Lam, HM;Hsieh, AC;Faltas, BM;Haffner, MC;Lee, JK; Combinatorial genetic strategy accelerates the discovery of cancer genotype-phenotype associations bioRxiv : the preprint server for biology 2023-04-14 [PMID: 37609344] (Flow Cytometry, Mouse)
• L Pontiggia, AK Ahuja, HK Yosef, D Rütsche, E Reichmann, U Moehrlen, T Biedermann Human Basal and Suprabasal Keratinocytes Are Both Able to Generate and Maintain Dermo-Epidermal Skin Substitutes in Long-Term In Vivo Experiments Cells, 2022-07-09;11(14):. 2022-07-09 [PMID: 35883599] (IHC, Human)
• B Kumar, AK Adebayo, M Prasad, ML Capitano, R Wang, P Bhat-Naksh, M Anjanappa, E Simpson, D Chen, Y Liu, JM Schilder, AB Colter, C Maguire, CJ Temm, G Sandusky, EH Doud, AB Wijeratne, AL Mosley, HE Broxmeyer, H Nakshatri Tumor collection/processing under physioxia uncovers highly relevant signaling networks and drug sensitivity Science Advances, 2022-01-12;8(2):eabh3375. 2022-01-12 [PMID: 35020422] (Flow Cytometry, Human)
• B Sadowska, J Rywaniak, A Cichocka, K Cichocka, J ?uchowski, U Wójcik-Boj, M Wi?ckowska, B Ró?alska Phenolic and Non-Polar Fractions of the Extracts from Fruits, Leaves, and Twigs of Elaeagnusrhamnoides (L.) A. Nelson-The Implications for Human Barrier Cells Molecules, 2020-05-09;25(9):. 2020-05-09 [PMID: 32397559] (Flow Cytometry, Human)
• Ouji Y, Ishizaka S, Nakamura-Uchiyama F, Okuzaki D, Yoshikawa M Partial maintenance and long-term expansion of murine skin epithelial stem cells by Wnt-3a in vitro. J Invest Dermatol, 2014-12-01;135(6):1598-608. 2014-12-01 [PMID: 25437427] (Flow Cytometry, Mouse)

Bioinformatics

• Gene Symbol: ITGA6