Insulin Receptor beta Antibody (C18C4)

Images

 
Western Blot: Insulin Receptor beta Antibody (C18C4) [NBP1-19192] - Lane 1: MW Marker, Lane 2: HeLa lysate, Lane 3: MCF-7 lysate, Lane 4: PC-12 lysate, Lane 5: 3T3 lysate.

Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Bv, Ha, Rb, ShSpecies Glossary
Applications WB
Clone
C18C4
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

Insulin Receptor beta Antibody (C18C4) Summary

Immunogen
Recombinant cytoplasmic domain of human Insulin Receptor beta
Specificity
Insulin Receptor beta (C18C4)
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
INSR
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
Publications
Read Publication using NBP1-19192.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 50% Glycerol
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein G purified

Alternate Names for Insulin Receptor beta Antibody (C18C4)

  • CD220 antigen
  • CD220
  • EC 2.7.10
  • EC 2.7.10.1
  • HHF5
  • insulin receptor
  • IR

Background

The Insulin Receptor (InsR) is a heterodimeric receptor tyrosine kinase with an extracellular alpha-chain, a transmembrane domain and an intracellular beta-chain. InsR is activated upon binding of the peptide hormone insulin, leading to autophosphorylation of tyrosine residues 1146, 1150, and 1151 in the activation loop of the beta-chain. Additional autophosphorylation sites such as tyrosine residues 960, 972, 1316, and 1322 regulate the assembly of signal transduction complexes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Insulin Receptor beta Antibody (NBP1-19192)(1)

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol INSR
Entrez