Species: Hu, Mu, Rt
Applications: WB, ICC/IF
Host: Rabbit Monoclonal
Species: Hu, Mu, Rt, Po, Bv, Ha, Rb, Sh
Host: Mouse Monoclonal
The Insulin Receptor (InsR) is a heterodimeric receptor tyrosine kinase with an extracellular alpha-chain, a transmembrane domain and an intracellular beta-chain. InsR is activated upon binding of the peptide hormone insulin, leading to autophosphorylation of tyrosine residues 1146, 1150, and 1151 in the activation loop of the beta-chain. Additional autophosphorylation sites such as tyrosine residues 960, 972, 1316, and 1322 regulate the assembly of signal transduction complexes.
|Product By Gene ID
- EC 220.127.116.11
- EC 2.7.10
- CD220 antigen
- insulin receptor
Bioinformatics Tool for Insulin Receptor beta
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