Species: Hu, Mu, Rt, Po, Bv, Ha, Rb, Sh
Host: Mouse Monoclonal
Species: Hu, Mu, Rt, Po, Bv, Ca, Pm, Xp
Host: Rabbit Polyclonal
The Insulin Receptor (InsR) is a heterodimeric receptor tyrosine kinase with an extracellular alpha-chain, a transmembrane domain and an intracellular beta-chain. InsR is activated upon binding of the peptide hormone insulin, leading to autophosphorylation of tyrosine residues 1146, 1150, and 1151 in the activation loop of the beta-chain. Additional autophosphorylation sites such as tyrosine residues 960, 972, 1316, and 1322 regulate the assembly of signal transduction complexes.
|Product By Gene ID
- EC 22.214.171.124
- EC 2.7.10
- CD220 antigen
- insulin receptor
Bioinformatics Tool for Insulin Receptor beta
Discover related pathways, diseases and genes to Insulin Receptor beta. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.