INMT Antibody (S08-9C6)

Western Blot: INMT Antibody (S08-9C6) [NBP3-19663] - Western blot detection of INMT in 3T3 cell lysates using NBP3-19663 (1:1000 diluted). Predicted band size: 29kDa. Observed band size: 29kDa.

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clone: S08-9C6
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 0.3 mg/ml

INMT Antibody (S08-9C6) Summary

• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: Recombinant protein of human INMT (Uniprot # O95050)
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: INMT
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1/1000-1/5000
• Theoretical MW: 29 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA
• Preservative: 0.01% Sodium Azide
• Concentration: 0.3 mg/ml
• Purity: Affinity purified

Alternate Names for INMT Antibody (S08-9C6)

• Amine N-methyltransferase
• Aromatic alkylamine N-methyltransferase
• Arylamine N-methyltransferase
• EC 2.1.1
• EC 2.1.1.49
• Indolamine N-methyltransferase
• indolethylamine N-methyltransferase
• MGC125940
• MGC125941
• nicotine N-methyltransferase

Background

INMT is a gene which codes for a protein that functions as a thioether S-methyltransferase which is necessary in the detoxification of selenium compounds and the catalyzation of the N-methylations of tryptamine and compounds with similar structures and has two isoforms with lengths of 263 and 262 amino acids, that both have a weight of approximately 29 kDa. Current studies are being done on diseases and disorders relating to this gene including appendicitis, homosydteine, thryoditis, and carcinoma. INMT has also been shown to interact with KCNMA1, FMO1, IDO1, AANAT, and ABP1 in pathways such as the tryptophan metabolism and selenocompound metabolism pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: INMT