Indian Hedgehog/Ihh Antibody (RM0145-3A11)

Product Discontinued

Indian Hedgehog/Ihh Antibody (RM0145-3A11) Summary

• Immunogen: Mouse recombinant protein of N-Terminal fragment of ihh protein
• Specificity: This was produced from a hybridoma (mouse myeloma) fused with spleen cells from a rat immunized with mouse recombinant protein of the N-Terminal fragment of ihh protein.
• Isotype: IgG2
• Clonality: Monoclonal
• Host: Rat
• Gene: IHH
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:1000

Reactivity Notes

Mouse.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from 0.2 um filtered PBS
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein G purified
• Reconstitution Instructions: Reconstitute with sterilized PBS to a final concentration of 0.5 mg/ml.

Alternate Names for Indian Hedgehog/Ihh Antibody (RM0145-3A11)

• BDA1
• BDA1Indian hedgehog homolog (Drosophila)
• HHG2
• HHG-2
• Ihh
• Indian hedgehog (Drosophila) homolog
• Indian hedgehog homolog
• indian hedgehog protein
• Indian Hedgehog

Background

Ihh is an intercellular signalling peptide essential for a variety of patterning events during development. It binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Ihh induces the expression of parathyroid hormone-related protein (PTHRP) and is implicated in endochondral ossification, possibly regulating the balance between growth and ossification of the developing bones.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IHH
• Entrez:
  • 3549(Human)