ILT7/CD85g/LILRA4 Antibody (656688) [Alexa Fluor® 405]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
656688
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 405
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

ILT7/CD85g/LILRA4 Antibody (656688) [Alexa Fluor® 405] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human LILRA4/CD85g/ILT7
Glu24-Asn446
Accession # P59901
Specificity
Detects human LILRA4/CD85g/ILT7 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) LILRA5, rhILT2, 3, 4, 5, or 6 is observed.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
LILRA4
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 0.25-1 ug/10^6 cells
Application Notes
Flow Cytometry: Please use 0.25-1 ug of conjugated antibody per 10e6 cells.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Buffer
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Preservative
0.09% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for ILT7/CD85g/LILRA4 Antibody (656688) [Alexa Fluor® 405]

  • CD85 antigen-like family member G
  • CD85g antigen
  • CD85g
  • ILT7
  • ILT-7
  • ILT7MGC129598
  • Immunoglobulin-like transcript 7
  • leukocyte immunoglobulin-like receptor subfamily A member 4
  • leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
  • leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member4
  • LILRA4
  • MGC129597

Background

LILRA4, also known as ILT7 and CD85g, is a 499 amino acid (aa) type I transmembrane glycoprotein that contains four Ig-like domains in its extracellular region. LILRA4 is selectively expressed on plasmacytoid dendritic cells (pDC). It binds to BST2/CD317 on bone marrow stromal cells and associates with the gamma subunit of Fc epsilon RI. This receptor complex transmits signals that inhibit the TLR-induced production of type I interferon. The LILRA4-mediated interactions between pDC and tumor cells similarly inhibit the production of proinflammatory cytokines and contribute to reduced anti-tumor immune responses. Alternate splicing of human LILRA4 generates an isoform that lacks the N-terminal 43 aa of the extracellular domain.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs for ILT7/CD85g/LILRA4 Antibody (FAB6287V) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 FAB6287U
Alexa Fluor 405 FAB6287V
Alexa Fluor 488 FAB6287G
Alexa Fluor 594 FAB6287T
Alexa Fluor 647 FAB6287R
Alexa Fluor 700 FAB6287N
Alexa Fluor 750 FAB6287S

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Bioinformatics

Gene Symbol LILRA4
Uniprot