ILT6/CD85e/LILRA3 Antibody [Alexa Fluor® 594]

• Reactivity: Hu
• Applications: CyTOF-ready, Flow
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Alexa Fluor 594

ILT6/CD85e/LILRA3 Antibody [Alexa Fluor® 594] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human LILRA3/CD85e
  Arg18-Glu439
  Accession # Q8N6C8
• Specificity: Detects human LILRA3/CD85e in direct ELISAs. In direct ELISAs, approximately 30% cross-reactivity with recombinant human (rh) ILT2, rhILT4, ILT5 is observed, and less than 5% cross-reactivity with rhLIR5 and rhLIR7 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Intracellular Staining by Flow Cytometry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for ILT6/CD85e/LILRA3 Antibody [Alexa Fluor® 594]

• CD85 antigen-like family member E
• CD85e antigen
• CD85e
• HM31
• HM43
• ILT6
• ILT-6
• ILT6CD85e
• Immunoglobulin-like transcript 6
• leucocyte immunoglobulin-like receptor
• Leukocyte immunoglobulin-like receptor 4
• leukocyte immunoglobulin-like receptor A3
• leukocyte immunoglobulin-like receptor subfamily A member 3
• leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member3
• LILRA3
• LIR4
• LIR4CD85E
• LIR-4HM43e3
• Monocyte inhibitory receptor HM43/HM31

Background

Human LIR-4 (Leukocyte Ig-like receptor #4; also ILT6 and LILRA3) is an Ig superfamily member that belongs to the leukocyte receptor complex/cluster. Mature LIR-4 is 416 amino acids in length and contains four C2-type Ig-like domains. Unlike other LIR family members, LIR-4 is actively secreted. At least one alternate splice form is known which shows a 64 amino acid deletion in the C-terminal half of the second Ig-like domain. Multiple alleles exist in human, and 5-10% of the population have a defective gene which produces no LIR-4 product. Rodent LIR-4 has not been reported.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.