ILT6/CD85e/LILRA3 Products

Description

Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function (see, e.g., LILRB1, MIM 604811). LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades (see LILRA1, MIM 604810). One member of subfamily A (LILRA3) lacks a transmembrane region and is presumed to be a soluble receptor (Borges et al., 1997 [PubMed 9548455]).[supplied by OMIM]

Bioinformatics

Entrez	11026 Human
Uniprot	NP_006856.2 Human
Product By Gene ID	11026
Alternate Names	CD85 antigen-like family member E CD85e antigen CD85e HM31 HM43 ILT6 ILT-6 ILT6CD85e Immunoglobulin-like transcript 6 leucocyte immunoglobulin-like receptor Leukocyte immunoglobulin-like receptor 4 leukocyte immunoglobulin-like receptor A3 leukocyte immunoglobulin-like receptor subfamily A member 3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member3 LILRA3 LIR4 LIR4CD85E LIR-4HM43e3 Monocyte inhibitory receptor HM43/HM31