ILT6/CD85e/LILRA3 Antibody [DyLight 350]

• Reactivity: Hu
• Applications: CyTOF-ready, Flow
• Clonality: Polyclonal
• Host: Goat
• Conjugate: DyLight 350

ILT6/CD85e/LILRA3 Antibody [DyLight 350] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human LILRA3/CD85e
  Arg18-Glu439
  Accession # Q8N6C8
• Specificity: Detects human LILRA3/CD85e in direct ELISAs. In direct ELISAs, approximately 30% cross-reactivity with recombinant human (rh) ILT2, rhILT4, ILT5 is observed, and less than 5% cross-reactivity with rhLIR5 and rhLIR7 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: LILRA3
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Intracellular Staining by Flow Cytometry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for ILT6/CD85e/LILRA3 Antibody [DyLight 350]

• CD85 antigen-like family member E
• CD85e antigen
• CD85e
• HM31
• HM43
• ILT6
• ILT-6
• ILT6CD85e
• Immunoglobulin-like transcript 6
• leucocyte immunoglobulin-like receptor
• Leukocyte immunoglobulin-like receptor 4
• leukocyte immunoglobulin-like receptor A3
• leukocyte immunoglobulin-like receptor subfamily A member 3
• leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member3
• LILRA3
• LIR4
• LIR4CD85E
• LIR-4HM43e3
• Monocyte inhibitory receptor HM43/HM31

Background

LILRA3, also known as Leukocyte immunoglobulin-like receptor subfamily A member 3, has 3 isoforms, a 439 amino acid isoform that is 47 kDa, a 375 amino acid isoform that is 40 kDa, and a 456 amino acid isoform that is 49; detected in B-cells, and at lower levels in natural killer (NK) cells, and in peripheral blood monocytes and lung; lacks a transmembrane region and is presumed to be a soluble receptor and may act as soluble receptor for class I MHC antigens. Studies on this protein have shown relationship with the following diseases and disorders: multiple sclerosis, rheumatoid arthritis, arthritis, ascariasis, trichuriasis, multiple sclerosis, rheumatism, interferon, and hepatitis c. This protein has been shown to interact with EWSR1 and USP46 proteins in osteoclast differentiation, defense response, and signal transduction pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LILRA3