IL1RAPL2 Antibody (320017) [Alexa Fluor® 405]

• Applications: WB
• Clone: 320017
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor 405

IL1RAPL2 Antibody (320017) [Alexa Fluor® 405] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse IL1RAPL2
  Asn18-Ala358
  Accession # Q9ERS6
• Specificity: Detects mouse IL1RAPL2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 25% cross‑reactivity with recombinant human (rh) IL1RAPL2 is observed and no cross-reactivity with recombinant mouse (rm) IL-1 R1,
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Purity Statement: Protein A or G purified

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

Interleukin 1 receptor accessory protein-like 2 (IL1RAPL2), also known as TIGIRR-1 and IL-1 R9, is a member of the IL-1 RI-like family of the IL-1 R/Toll-like receptor superfamily. IL1RAPL2 is a type I transmembrane protein that contains three Ig-like domains in its extracellular region and one intracellular TIR domain. IL1RAPL2 is expressed in the central nervous system, and its deletion is associated with some forms of X-linked mental retardation. An alternately spliced variant lacks the transmembrane and cytoplasmic regions. Within their extracellular domains, mouse IL1RAPL2 shares 99% amino acid sequence identity with human IL1RAPL2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.