IL-9R Antibody (33449) [Alexa Fluor® 350]

• Applications: WB
• Clone: 33449
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 350

IL-9R Antibody (33449) [Alexa Fluor® 350] Summary

• Immunogen: S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL-9 R
  Ser41-Pro270
  Accession # Q01113
• Specificity: Detects human IL-9 R in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross‑reactivity with recombinant human (rh) IL‑4 R , rhIL-5 R alpha , rhIL-5 R beta , rhIL-13 R alpha 1, rhIL-13 R alpha 2, and recombinant mouse IL‑9&
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

The specific high affinity functional IL-9 receptor complex consists of a ligand-specific IL-9 R( alpha ) type I transmembrane subunit and the common gamma chain that is shared with the receptors for IL-2, IL-4, IL-7 and IL-15. Both the IL-9 R subunit and the common gamma chain are members of the hematopoietin receptor superfamily. Human and mouse IL-9 receptors share 53% amino acid sequence identity, and contain 468 and 533 amino acids, respectively. As a result of alternative splicing, cDNA clones encoding isoforms of IL-9 R, including a putative soluble form, have also been identified. Cells known to express IL-9 R include T cells, neutrophils, mast cells and macrophages.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.