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MAB002, open histogram), followed by Phycoerythrin-conjugated Anti-Mouse IgG F(ab')2Secondary Antibody (Catalog # F0102B)." class="big_lightbox" target="_blank">
209-IL) stimulates proliferation in the MO7e human megakaryocytic leukemic cell line in a dose-dependent manner (orange line). Proliferation elicited by Recombinant Human IL-9 (2 ng/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-Human IL-9 R Subunit Mono-clonal Antibody (Catalog # MAB290). The ND50 is typically 2-4 µg/mL." class="big_lightbox" target="_blank">
The protein encoded by the IL9R gene is a cytokine receptor that specifically mediates the biological effects ofinterleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor,gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of thisreceptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologicresponses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested anassociation of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 havebeen described. Alternatively spliced transcript variants have been found for this gene. (provided by RefSeq)
![Flow Cytometry IL-9R Antibody (33423) [Unconjugated]](http://images.novusbio.com/images/antibody/IL-9_R_MAB290_Flow_Cytometry_8389.jpg)
![Neutralization IL-9R Antibody (33423) [Unconjugated]](http://images.novusbio.com/images/antibody/IL-9_R_MAB290_Block_Neutralize_9132.jpg)
