IL-17B Antibody [Allophycocyanin]

• Reactivity: Mu
• Applications: WB, B/N, CyTOF-ready, ELISA, ELISA(Cap), ELISA(Det), Flow
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Allophycocyanin

IL-17B Antibody [Allophycocyanin] Summary

• Immunogen: E. coli-derived recombinant mouse IL-17B
  His21-Phe180
  Accession # Q9QXT6
• Specificity: Detects mouse IL‑17B in ELISAs and Western blots. In sandwich immunoassays, approximately 40% cross-reactivity with recombinant human IL-17B is observed and less than 0.3% cross-reactivity with recombinant mouse (rm) IL‑17, rmIL-17C, rmIL-17D, rmIL-17E, and
  rmIL‑17F is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: IL17B
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Blockade of Receptor-ligand Interaction
  • CyTOF-ready
  • ELISA Capture (Matched Antibody Pair)
  • ELISA Detection (Matched Antibody Pair)
  • ELISA Standard (Matched Pair)
  • Intracellular Staining by Flow Cytometry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Alternate Names for IL-17B Antibody [Allophycocyanin]

• Cytokine Zcyto7
• cytokine-like protein ZCYTO7
• IL17B
• IL-17B
• IL-17Binterleukin-17 beta
• IL20
• IL-20interleukin-17B
• interleukin 17B
• interleukin 20
• Interleukin-20
• MGC138900
• MGC138901
• neuronal interleukin-17 related factor
• Neuronal interleukin-17-related factor
• NIRF
• ZCYTO7interleukin-20

Background

Recently, a number of cytokines belonging to the interleukin (IL)-17 family have been identified. These are IL-17B, IL-17C, and IL-17E. Like IL-17, IL-17B, C, and E are able to induce proinflammatory responses but don't bind to the IL-17 receptor suggesting additional IL-17R related receptors might exist. IL-17E induces activation of NF-kB pathway and like IL-17 also induces production of IL-8. IL-17Rh1 mRNA is highly expressed in kidney and liver and at moderate level in small intestine, colon, and brain.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IL17B