IL-16 Antibody [Alexa Fluor® 532] Summary
| Immunogen |
Mouse myeloma cell line NS0-derived recombinant mouse IL-16 Ser1205-Ser1322 Accession # O54824 |
| Specificity |
Detects mouse IL-16 in direct ELISAs and Western blots. In direct ELISAs, approximately 50% cross-reactivity with recombinant human IL‑16 is observed. |
| Isotype |
IgG |
| Clonality |
Polyclonal |
| Host |
Goat |
| Purity Statement |
Antigen Affinity-purified |
| Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Packaging, Storage & Formulations
| Storage |
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied |
| Buffer |
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide |
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for IL-16 Antibody [Alexa Fluor® 532]
Background
Interleukin 16, also known as lymphocyte chemoattractant factor (LCF), refers to the C-terminal peptide of mouse pro-IL-16 or neuronal IL-16, which are nuclear and cytoplasmic PD2 domain containing proteins. The C-termini of these proteins are cleaved by Caspase-3, resulting in the release of secreted IL-16. Mature IL-16 has been shown to bind the cell surface receptor CD4 and function as an immunomodulatory cytokine. The C-terminal peptide of human and mouse IL-16 share approximately 86% amino acid sequence identity.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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