Species: Hu
Applications: WB, IHC, CyTOF-ready, Flow, ICC/IF
Host: Goat Polyclonal
Species: Mu
Applications: WB
Host: Rat Monoclonal
Species: Hu
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Mu
Applications: ELISA
Host: Rabbit Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Mu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: Bioactivity
Species: Mu
Applications: PAGE, Bioactivity
Species: Hu
Applications: PAGE, Bioactivity
Description
Interleukin-16 (IL-16, also known as lymphocyte chemoattractant factor (LCF)) is a CD8+ T cell-derived cytokine. It acts as a chemoattractant for CD4+ T-cells, monocytes and eosinophils. IL-16 has also been shown to suppress HIV-1 replication in vitro. It is expressed as a precursor molecule (pro-IL-16) in various tissues including spleen, thymus, lymph nodes, peripheral leukocytes, bone marrow and cerebellum. The active form is assumed to be a proteolytic cleavage product of pro-IL-16 existing, under physiological conditions, predominantly as a noncovalently linked multimer. The sequence and structure of IL-16 is conserved across species, human and murine IL-16 show significant cross-species reactivity.
Bioinformatics
Entrez |
Mouse Human |
Uniprot |
Human Human Human Human Human Human |
Product By Gene ID |
3603 |
Alternate Names |
- FLJ16806
- FLJ42735
- FLJ44234
- HsT19289
- IL-16
- interleukin 16 (lymphocyte chemoattractant factor)
- LCFprIL-16
- lymphocyte chemoattractant factor
- neuronal interleukin 16
- NIL16
- PRIL16
- prointerleukin 16
- pro-interleukin-16
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