IL-16 Products

Description

Interleukin-16 (IL-16, also known as lymphocyte chemoattractant factor (LCF)) is a CD8+ T cell-derived cytokine. It acts as a chemoattractant for CD4+ T-cells, monocytes and eosinophils. IL-16 has also been shown to suppress HIV-1 replication in vitro. It is expressed as a precursor molecule (pro-IL-16) in various tissues including spleen, thymus, lymph nodes, peripheral leukocytes, bone marrow and cerebellum. The active form is assumed to be a proteolytic cleavage product of pro-IL-16 existing, under physiological conditions, predominantly as a noncovalently linked multimer. The sequence and structure of IL-16 is conserved across species, human and murine IL-16 show significant cross-species reactivity.

Bioinformatics

Entrez	16170 Mouse 3603 Human
Uniprot	AAC12732 Human AAH40272 Human AAH40272.1 Human NM_004513 Human NP_004504 Human Q14005 Human
Product By Gene ID	3603
Alternate Names	FLJ16806 FLJ42735 FLJ44234 HsT19289 IL-16 interleukin 16 (lymphocyte chemoattractant factor) LCFprIL-16 lymphocyte chemoattractant factor neuronal interleukin 16 NIL16 PRIL16 prointerleukin 16 pro-interleukin-16

Diseases related to IL-16

Discover more about diseases related to IL-16.

Malignant Neoplasms
Neoplasms
Inflammation
Arthritis
Malignant Neoplasm Of Prostate
Hiv Infections
Cholangiocarcinoma
Malignant Neoplasm Of Breast
Carcinoma
Immunologic Deficiency Syndromes
Hepatitis
Diabetes Mellitus
Contact Dermatitis
Prostatic Neoplasms
Diabetes Mellitus, Insulin-dependent
Dermatitis, Allergic Contact
Allergy
Chronic Lymphocytic Leukemia
Dermatitis
Autoimmune Reaction

Pathways for IL-16

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Cell Activation
Pathogenesis
Sensitization
Cell Migration
Chemokine Production
Cell Development
T Cell Activation
Dna Repair
Lymphocyte Migration
Virulence
Localization
Chemotaxis
Cell Cycle
Ubiquitin Cycle
Tissue Remodeling
Mesoderm Development

Research Areas for IL-16

Find related products by research area and learn more about each of the different research areas below.

Biologically Active Proteins
Cytokine Research
Immunology
Innate Immunity

Bioinformatics Tool for IL-16

Discover related pathways, diseases and genes to IL-16. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.