IL-11 Antibody (MM0361-9T27) [Alexa Fluor™ Plus 647]

• Reactivity: Hu
• Applications: WB, B/N
• Clone: MM0361-9T27
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 647

IL-11 Antibody (MM0361-9T27) [Alexa Fluor™ Plus 647] Summary

• Immunogen: Human recombinant IL-11
• Isotype: IgG2
• Clonality: Monoclonal
• Host: Mouse
• Gene: IL11
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Block/Neutralize
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for IL-11 Antibody (MM0361-9T27) [Alexa Fluor™ Plus 647]

• Adipogenesis inhibitory factor
• AGIF
• AGIFoprelvekin
• IL11
• IL-11
• IL-11Oprelvekin
• interleukin 11
• interleukin-11
• Oprelvekin

Background

Interleukin 11 is a pleiotropic cytokine produced by mesenchymal-derived adherent cells. IL11 shares many functions of IL6 and LIF, including potentiation of megakaryocyte activity, enhancement of human myeloma cell proliferation, and enhancement of hepatic acute phase protein production.Interleukin 11 directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells, and induces megakaryocyte maturation resulting in increased platelet production. Clinically it is used to prevent severe thrombocytopenia and the reduction of the need for platelet transfusion following myelosuppressive chemotherapy.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IL11