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218-IL) stimulates proliferation in the T11 mouse plasmacytoma cell line in a dose-dependent manner (orange line). Proliferation elicited by Recombinant Human IL-11 (1 ng/mL) is neutralized (green line) by increasing concen-trations of Mouse Anti-Human IL-11 Monoclonal Antibody (Catalog # MAB218). The ND50 is typically ≤ 8 µg/mL." class="big_lightbox" target="_blank">
218-IL) was serially diluted and captured by Mouse Anti-Human IL‑11 Monoclonal Antibody (Catalog # MAB618) coated on a Clear Polystyrene Microplate (Catalog # DY990). Goat Anti-Human IL‑11 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF-218-NA) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998)" class="big_lightbox" target="_blank">
418-ML) stimulates proliferation in the T11 mouse plasmacytoma cell line in a dose-dependent manner (orange line). Proliferation elicited by Recombinant Mouse IL‑11 (0.75 ng/mL) is neutralized (green line) by increasing concentrations of Rat Anti-Mouse IL‑11 Monoclonal Antibody (Catalog # MAB418). The ND50 is typically 0.5-2.0 µg/mL." class="big_lightbox" target="_blank">
Interleukin 11 is a pleiotropic cytokine produced by mesenchymal-derived adherent cells. IL11 shares many functions of IL6 and LIF, including potentiation of megakaryocyte activity, enhancement of human myeloma cell proliferation, and enhancement of hepatic acute phase protein production.Interleukin 11 directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells, and induces megakaryocyte maturation resulting in increased platelet production. Clinically it is used to prevent severe thrombocytopenia and the reduction of the need for platelet transfusion following myelosuppressive chemotherapy.
![Neutralization IL-11 Antibody (22626) [Unconjugated]](http://images.novusbio.com/images/antibody/IL-11_MAB218_Block_Neutralize_9080.jpg)
![ELISA IL-11 Antibody (22616) [Unconjugated]](http://images.novusbio.com/fullsize/mab618_human-il-11-mab-clone-22616-41202412513826.jpg)
![N/A IL-11 [HRP]](http://images.novusbio.com/fullsize/elisa/DATA_IL11_D1100_ELISA_529.jpg)
![N/A IL-11 [Biotin]](http://images.novusbio.com/fullsize/elisa/DATA_IL11_DY218_ELISA_1780.jpg)
![N/A IL-11 [Biotin]](http://images.novusbio.com/fullsize/elisa/DATA_IL11_DY418_ELISA_2015.jpg)
![SEC-MALS IL-11 [Unconjugated]](http://images.novusbio.com/fullsize/218-il_recombinant-human-il-11-protein-sec-mals-4420248492..jpg)
![SEC-MALS IL-11 [Unconjugated]](http://images.novusbio.com/fullsize/10836-il_recombinant-human-il-11-cho-expressed-protein-cf-sec-mals-342024987..jpg)
![Bioactivity IL-11 [Unconjugated]](http://images.novusbio.com/fullsize/11585-il_recombinant-mouse-il-11-protein-cf-bioactivity-2282024113056.jpg)
![Western Blot IL-11 Antibody (22626) [Unconjugated]](http://images.novusbio.com/fullsize/mab218_human-il-11-mab-clone-22626-4120241033196.jpg)
![Western Blot IL-11 Antibody (22626) [Unconjugated]](http://images.novusbio.com/fullsize/mab218_human-il-11-mab-clone-22626-41202410325589.jpg)
![ELISA IL-11 Antibody (22616) [Unconjugated]](http://images.novusbio.com/images/mab618_human-il-11-mab-clone-22616-elisa-639201776265323373.jpg)
![N/A IL-11 [HRP]](http://images.novusbio.com/fullsize/elisa/DATA_IL11_D1100_ELISA_530.jpg)
![N/A IL-11 [HRP]](http://images.novusbio.com/fullsize/elisa/IL-11_D1100_ELISA_10.jpg)
![Bioactivity IL-11 [Unconjugated]](http://images.novusbio.com/fullsize/10836-il_recombinant-human-il-11-cho-expressed-protein-cf-2162021102548.jpg)
![SDS-Page IL-11 [Unconjugated]](http://images.novusbio.com/fullsize/10836-il_recombinant-human-il-11-cho-expressed-protein-cf-sds-page-2462021135427.jpg)
![SDS-Page IL-11 [Unconjugated]](http://images.novusbio.com/fullsize/11585-il_recombinant-mouse-il-11-protein-cf-sds-page-2282024112444.jpg)
