Detection of IL-1, beta in two-site immunoassay. We recommend using mixture of NB120-8319 and NB100-73053 for coating and NB100-73054 for labeling. For IHC on frozen and parafin embedded sections, use formalin with 2.5% glutaraldehyde as a fixative.
Read Publication using NB120-8319 in the following applications:
Alternate Names for IL-1 beta/IL-1F2 Antibody (6E10)
interleukin 1, beta
preinterleukin 1 beta
Interleukin 1 (IL1), originally known as lymphocyte activating factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin 2. IL1 is primarily released from stimulated macrophages and monocytes, but also is released from several other cell types, and is thought to play a key role in inflammatory and immune responses. The two closely related agents, interleukin1 alpha (IL1 alpha) and interleukin1 beta (IL1 beta) bind to the same cell surface receptor, elicit nearly identical biological responses and share 25% homology in their amino acid sequence.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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