IL-1 alpha/IL-1F1 Antibody (40508) [DyLight 488] Summary
Immunogen |
E. coli-derived recombinant mouse IL-1 alpha /IL-1F1 Ser115-Ser270 Accession # P01582 |
Specificity |
Detects mouse IL-1 alpha /IL-1F1 in ELISAs. In ELISAs, less than 1% cross-reactivity with recombinant rat IL‑1 alpha /IL‑1F1, recombinant porcine IL‑1 alpha /IL‑1F1, and recombinant human IL‑1 alpha /IL‑1F1 is observed. |
Isotype |
IgG2b |
Clonality |
Monoclonal |
Host |
Rat |
Gene |
IL1A |
Purity |
Protein A or G purified from hybridoma culture supernatant |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- ELISA Capture (Matched Antibody Pair)
- ELISA Detection (Matched Antibody Pair)
- ELISA Standard (Matched Pair)
- Neutralization
|
Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
50mM Sodium Borate |
Preservative |
0.05% Sodium Azide |
Purity |
Protein A or G purified from hybridoma culture supernatant |
Notes
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
Alternate Names for IL-1 alpha/IL-1F1 Antibody (40508) [DyLight 488]
Background
Interleukin-1 alpha (IL-1a, lymphocyte activating factor (LAF), hematopoietin-1, endogeneous pyrogen, mononuclear cell factor) is a pleiotropic pro-inflammatory cytokine produced in a variety of cells, including monocytes, macrophages and epithelial cells. It is involved in inflammatory and immune responses and regulation of hematopoiesis. It may therefore be of clinical use following massive immunosuppression and chemotherapy. Recombinant human IL-1a is a single non-glycosylated polypetide chain of 159 amino acids with a MW of 18 kDa. Sequence conservation of the mature protein among various species is 60% -70%, human IL-1 has been found to be biologically active on murine cell lines.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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FAQs for IL-1 alpha/IL-1F1 Antibody (FAB400K) (0)
Secondary Antibodies
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Isotype Controls
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