Iduronate 2-Sulfatase/IDS Antibody (331320) [mFluor Violet 610 SE]

• Reactivity: Hu
• Applications: WB
• Clone: 331320
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 610 SE

Iduronate 2-Sulfatase/IDS Antibody (331320) [mFluor Violet 610 SE] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Iduronate 2-Sulfatase/IDS
  Ser26-Pro550
  Accession # P22304
• Specificity: Detects human Iduronate 2-Sulfatase/IDS in direct ELISAs and Western blots. In direct ELISAs and Western blots, this antibody does not cross‑react with recombinant mouse Iduronate 2-Sulfatase/IDS.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: IDS
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Iduronate 2-Sulfatase/IDS Antibody (331320) [mFluor Violet 610 SE]

• Alpha-L-iduronate sulfate sulfatase
• EC 3.1.6.13
• IDS
• iduronate 2-sulfatase 14 kDa chain
• iduronate 2-sulfatase 42 kDa chain
• iduronate 2-sulfatase
• idursulfase
• MPS2
• S
• SIDS

Background

Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence homology with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. A splice variant of this gene has been described.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IDS