Hu, Mu, Rt, Ca, PmApplications:
WB, Flow, ICC/IF, IHC, IHC-PHost:
Species: Hu, Mu, Rt, Pm
Applications: WB, Flow, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
Applications: Enzyme Activity
Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence homology with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. A splice variant of this gene has been described.
|Product By Gene ID
- iduronate 2-sulfatase 14 kDa chain
- EC 220.127.116.11
- Alpha-L-iduronate sulfate sulfatase
- iduronate 2-sulfatase 42 kDa chain
- iduronate 2-sulfatase
Bioinformatics Tool for Iduronate 2-Sulfatase/IDS
Discover related pathways, diseases and genes to Iduronate 2-Sulfatase/IDS. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.