ICA1 Antibody

Western Blot: ICA1 Antibody [H00003382-D01P] - Analysis of ICA1 expression in transfected 293T cell line by ICA1 polyclonal antibody.Lane 1: ICA1 transfected lysate(54.60 KDa).Lane 2: Non-transfected lysate.

Product Discontinued

ICA1 Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: ICA1 (AAH08640.1, 1 a.a. - 482 a.a.) full-length human protein. MSGHKCYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALCFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELDPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHFWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPSQLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVAGTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQTGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHELLNA
• Specificity: ICA1 - islet cell autoantigen 1, 69kDa,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ICA1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for ICA1 Antibody

• diabetes mellitus type I autoantigen
• ICA1
• ICA69
• ICAp69
• ICAp69Islet cell autoantigen p69,69 kDa islet cell autoantigen
• islet cell autoantigen 1 (69kD)
• islet cell autoantigen 1 isoform
• islet cell autoantigen 1
• islet cell autoantigen 1, 69kDa
• p69

Background

This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ICA1
• Entrez:
  • 3382(Human)
• Uniprot:
  • AAH08640.1(Human)