IBTK Antibody Blocking Peptide

• Reactivity: Hu
• Applications: AC

IBTK Antibody Blocking Peptide Summary

• Description: A Human IBTK antibody blocking peptide
  
  Source: Synthetic (Accession #: Q9P2D0)
  
  Store vial at -20C prior to opening. Aliquot contents and freeze at -20C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4C as an undiluted liquid. Dilute only prior to immediate use.
• Source: Synthetic
• Protein/Peptide Type: Antibody Blocking Peptide
• Gene: IBTK
• Purity: >95%

Applications/Dilutions

• Dilutions:
  • Antibody Competition
• Application Notes: This product should be used at 1.0 ug per 1.0 ul of antiserum in per assay.

Packaging, Storage & Formulations

• Storage: Store at -20C short term. Aliquot and store at -80C long term. Avoid freeze-thaw cycles.
• Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
• Preservative: No Preservative
• Purity: >95%

Alternate Names for IBTK Antibody Blocking Peptide

• Bruton agammaglobulinemia tyrosine kinase inhibitor
• BTK-binding protein
• BTKI
• DKFZP564B116
• IBtk
• inhibitor of Bruton agammaglobulinemia tyrosine kinase
• inhibitor of Bruton tyrosine kinase
• inhibitor of Bruton's tyrosine kinase
• inhibitor of Bruton's tyrosine kinase-alpha
• inhibitor of Bruton's tyrosine kinase-beta
• inhibitor of Bruton's tyrosine kinase-gamma
• KIAA1417
• MGC142256
• MGC142258
• RP1-93K22.1

Background

IBTK is encoded by this gene binds to Bruton's tyrosine kinase (BTK) and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: IBTK
• Uniprot:
  • Q9P2D0(Human)