IBTK Antibody [Alexa Fluor® 488]

• Reactivity: Hu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Alexa Fluor 488

IBTK Antibody [Alexa Fluor® 488] Summary

• Immunogen: The immunogen for this product maps to a region between residue 1050 and 1100 of human Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase, using the numbering given in entry NP_056340.2 (GeneID 25998).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: IBTK
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for IBTK Antibody [Alexa Fluor® 488]

• Bruton agammaglobulinemia tyrosine kinase inhibitor
• BTK-binding protein
• BTKI
• DKFZP564B116
• IBtk
• inhibitor of Bruton agammaglobulinemia tyrosine kinase
• inhibitor of Bruton tyrosine kinase
• inhibitor of Bruton's tyrosine kinase
• inhibitor of Bruton's tyrosine kinase-alpha
• inhibitor of Bruton's tyrosine kinase-beta
• inhibitor of Bruton's tyrosine kinase-gamma
• KIAA1417
• MGC142256
• MGC142258
• RP1-93K22.1

Background

IBTK is encoded by this gene binds to Bruton's tyrosine kinase (BTK) and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IBTK