Independent Antibodies: Western Blot: IBTK Antibody [NBP1-50033] - Detection of Human IBtk by Western Blot and Immunoprecipitation. Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB; 1 mg for IP, 20% ...read more
The immunogen for this product maps to a region between residue 1050 and 1100 of human Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase, using the numbering given in entry NP_056340.2 (GeneID 25998).
Immunogen affinity purified
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inhibitor of Bruton agammaglobulinemia tyrosine kinase
inhibitor of Bruton tyrosine kinase
inhibitor of Bruton's tyrosine kinase
inhibitor of Bruton's tyrosine kinase-alpha
inhibitor of Bruton's tyrosine kinase-beta
inhibitor of Bruton's tyrosine kinase-gamma
The protein encoded by this gene binds to Bruton's tyrosine kinase (BTK) and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. [provided by RefSeq]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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