Human WISP-1/CCN4 DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human WISP-1/CCN4 DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: WISP1

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human WISP-1/CCN4 DuoSet ELISA, 15 Plate

• CCN family member 4
• CCN4
• CCN4WISP1tc
• WISP1
• WISP-1
• WISP1c
• WISP1i
• WNT1 induced secreted protein 1
• WNT1 inducible signaling pathway protein 1
• Wnt-1 inducible signaling pathway protein 1
• wnt-1 signaling pathway protein 1
• Wnt-1-induced secreted protein
• WNT1-inducible-signaling pathway protein 1

Background

WISP-1 belongs to the CCN (CTGF/CYR61/NOV) family of secreted proteins that share a common multimodular organization. Each family member has an IGFBP domain, a von Willebrand type C domain, a thrombospondin 1 domain and a C-terminal cysteine knot domain. Depending on cell context, WISP-1 can either promote or inhibit tumorigenesis.

Publications for WISP-1/CCN4 (DY1627)(5)

Publications using DY1627

• DJ Klinke Ii, A Fernandez, W Deng, A Razazan, H Latifizade, AC Pirkey Data-driven learning how oncogenic gene expression locally alters heterocellular networks Nature Communications, 2022-04-13;13(1):1986. 2022-04-13 [PMID: 35418177] (Mouse)
• O Pivovarova, J Loske, S Hornemann, M Markova, N Seebeck, A Rosenthal, F Klauschen, JP Castro, R Buschow, T Grune, V Lange, N Rudovich, DM Ouwens Hepatic Wnt1 Inducible Signaling Pathway Protein 1 (WISP-1/CCN4) Associates with Markers of Liver Fibrosis in Severe Obesity Cells, 2021-04-29;10(5):. 2021-04-29 [PMID: 33946738] (Human)
• H Shailesh, KS Siveen, S Sif Protein arginine methyltransferase 5 (PRMT5) activates WNT/&beta-catenin signalling in breast cancer cells via epigenetic silencing of DKK1 and DKK3 Journal of Cellular and Molecular Medicine, 2021-01-18;0(0):. 2021-01-18 [PMID: 33462997] (Human)
• W Deng, A Fernandez, SL McLaughlin, DJ Klinke WNT1-inducible signaling pathway protein 1 (WISP1/CCN4) stimulates melanoma invasion and metastasis by promoting the epithelial - mesenchymal transition J. Biol. Chem., 2019-02-05;0(0):. 2019-02-05 [PMID: 30723155] (Human)
• Li , Wen-Feng, Zhang , Li, Li , Hai-Ying, Zheng , Si-Si, Zhao , Liang WISP-1 contributes to fractionated irradiation-induced radioresistance in esophageal carcinoma cell lines and mice. PLoS ONE, 2014-04-11;9(4):e94751. 2014-04-11 [PMID: 24728101] (Human)

FAQs for WISP-1/CCN4 (DY1627). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: WISP1