WISP-1/CCN4 Products

Antibodies
WISP-1/CCN4 Antibody
WISP-1/CCN4 Antibody
AF1680
Species: Mu
Applications: WB, IHC
Host: Sheep Polyclonal
Conjugate Catalog # Availability Size Price
WISP-1/CCN4 Antibody
WISP-1/CCN4 Antibody
AF1627
Species: Hu
Applications: WB, IHC
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
WISP-1/CCN4 Antibody
WISP-1/CCN4 Antibody
NBP1-31230
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
WISP-1/CCN4 Overexpression Ly ...
WISP-1/CCN4 Overexpression Lysate ...
H00008840-T01
Species: Hu
Applications: WB
WISP-1/CCN4 Overexpression Ly ...
WISP-1/CCN4 Overexpression Lysate ...
NBL1-17856
Applications: WB
WISP-1/CCN4 Overexpression Ly ...
WISP-1/CCN4 Overexpression Lysate ...
NBL1-17857
Applications: WB
Proteins
Human WISP-1/CCN4 Biologicall ...
Human WISP-1/CCN4 Biologically Act...
NBP2-36591
Species: Hu
Applications: Func, PAGE
Human WISP-1/CCN4 Biologicall ...
Human WISP-1/CCN4 Biologically Act...
NBP2-36503
Species: Hu
Applications: PAGE
WISP-1/CCN4 Recombinant Prote ...
WISP-1/CCN4 Recombinant Protein
H00008840-P01
Species: Hu
Applications: WB, ELISA, PA

Description

WISP1 encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. It is expressed at a high level in fibroblast cells, and overexpressed in colon tumors. The encoded protein binds to decorin and biglycan, two members of a family of small leucine-rich proteoglycans present in the extracellular matrix of connective tissue, and possibly prevents the inhibitory activity of decorin and biglycan in tumor cell proliferation. It also attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase. It is 83% identical to the mouse protein at the amino acid level. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq]

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Human
Mouse
Product By Gene ID 8840
Alternate Names
  • WNT1-inducible-signaling pathway protein 1
  • WISP1c
  • WNT1 induced secreted protein 1
  • CCN family member 4
  • wnt-1 signaling pathway protein 1
  • WISP-1
  • Wnt-1 inducible signaling pathway protein 1
  • Wnt-1-induced secreted protein
  • CCN4WISP1tc
  • WISP1i
  • WNT1 inducible signaling pathway protein 1

Research Areas for WISP-1/CCN4

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
DNA Repair

PTMs for WISP-1/CCN4

Learn more about PTMs related to WISP-1/CCN4.

Phosphorylation
Glycosylation
Methylation

Bioinformatics Tool for WISP-1/CCN4

Discover related pathways, diseases and genes to WISP-1/CCN4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.