Human ULBP-3 DuoSet ELISA, 5 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human ULBP-3 DuoSet ELISA, 5 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: ULBP3

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human ULBP-3 DuoSet ELISA, 5 Plate

• NKG2D ligand 3
• RAET1N
• UL16 binding protein 3
• ULBP3
• ULBP-3

Background

ULBP-1, -2, and -3 were originally identified as ligands for the human cytomegalovirus glycoprotein UL16 and designated UL16-binding proteins (ULBP). These proteins are distantly related to major histocompatibility class I (MHC I) molecules, possessing the alpha 1 and alpha 2 Ig-like domains, but lacking the alpha 3 domain. Unlike MHC Class I, they have no capacity to bind peptide or interact with beta2-microglobulin. ULBP-1, -2, and -3 are known to bind to human NKG2D, an activating receptor expressed on NK cells, NKT cells, gamma delta T cells, and CD8+ alpha beta T cells.

Publications for ULBP-3 (DY1517-05)(3)

Publications using DY1517-05

• Vulpis, E;Loconte, L;Cassone, C;Antonangeli, F;Caracciolo, G;Masuelli, L;Fazio, F;Petrucci, MT;Fionda, C;Soriani, A;Cerboni, C;Cippitelli, M;Santoni, A;Zingoni, A; Cross-Dressing of Multiple Myeloma Cells Mediated by Extracellular Vesicles Conveying MIC and ULBP Ligands Promotes NK Cell Killing International journal of molecular sciences 2023-05-30 [PMID: 37298418] (Human)
• Expression and prognostic significance of unique ULBPs in pancreatic cancer Onco Targets Ther, 2016-08-25;9(0):5271-9. 2016-08-25 [PMID: 27621649] (Human)
• Cox S, Laza-Briviesca R, Pearson H, Soria B, Gibson D, Gomez S, Madrigal J, Saudemont A Umbilical cord blood plasma contains soluble NKG2D ligands that mediate loss of natural killer cell function and cytotoxicity. Eur J Immunol, 2015-06-09;45(8):2324-34. 2015-06-09 [PMID: 25991034] (Human)

Bioinformatics

• Gene Symbol: ULBP3