Human Total HGFR/c-MET DuoSet IC ELISA, 2 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human Total HGFR/c-MET DuoSet IC ELISA, 2 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: MET

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Total HGFR/c-MET DuoSet IC ELISA, 2 Plate

• AUTS9
• cMET
• c-MET
• EC 2.7.10
• EC 2.7.10.1
• hepatocyte growth factor receptor
• HGF R
• HGF receptor
• HGF/SF receptor
• HGFR
• Met (c-Met)
• met proto-oncogene (hepatocyte growth factor receptor)
• met proto-oncogene tyrosine kinase
• MET
• oncogene MET
• Proto-oncogene c-Met
• RCCP2
• Scatter factor receptor
• SF receptor
• Tyrosine-protein kinase Met

Background

HGF receptor, a product of the proto-oncogene c-met, is a heterodimeric transmembrane glycoprotein that is a receptor-type tyrosine kinase. c-MET is synthesized as a single-chain precursor (pr170) which undergoes post-translational glycosylation and proteolytic cleavage to give rise to the heterodimeric mature form.

Publications for HGFR/c-MET (DYC358-2)(4)

Publications using DYC358-2

• A Amaro, M Croce, S Ferrini, G Barisione, M Gualco, P Perri, U Pfeffer, MJ Jager, SE Coupland, C Mosci, G Filaci, M Fabbi, P Queirolo, R Gangemi Potential Onco-Suppressive Role of miR122 and miR144 in Uveal Melanoma through ADAM10 and C-Met Inhibition Cancers (Basel), 2020-06-04;12(6):. 2020-06-04 [PMID: 32512881] (Human)
• Oh , Young Mi, Lee , Saet Byo, Choi , Jaehyun, Suh , Hye-Youn, Shim , Seonhui, Song , Yun-Jeon, Kim , Bogyou, Lee , Ji Min, Oh , Seung Ja, Jeong , Yunju, Cheong , Kwang Ho, Song , Paul H, Kim , Kyung-Ah USP8 modulates ubiquitination of LRIG1 for Met degradation. Sci Rep, 2014-05-15;4(0):4980. 2014-05-15 [PMID: 24828152] (Human)
• Fu , Le, Guo , Wei, Liu , Bingshan, Sun , Linlin, Bi , Zhenghon, Zhu , Li, Wang , Xinyan, Liu , Bin, Xie , Qian, Li , Ke Shedding of c-Met ectodomain correlates with c-Met expression in non-small cell lung cancer. Biomarkers, 2013-03-01;18(2):126-35. 2013-03-01 [PMID: 23410046] (Human)
• Xu L, Nilsson MB, Saintigny P, Cascone T, Herynk MH, Du Z, Nikolinakos PG, Yang Y, Prudkin L, Liu D, Lee JJ, Johnson FM, Wong KK, Girard L, Gazdar AF, Minna JD, Kurie JM, Wistuba II, Heymach JV Epidermal growth factor receptor regulates MET levels and invasiveness through hypoxia-inducible factor-1alpha in non-small cell lung cancer cells. Oncogene, 2010-02-15;29(18):2616-27. 2010-02-15 [PMID: 20154724] (Human)

Bioinformatics

• Gene Symbol: MET