Human Total Cathepsin S DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human Total Cathepsin S DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: CTSS

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Total Cathepsin S DuoSet ELISA, 15 Plate

• Cathepsin S
• CTSS
• EC 3.4.22
• EC 3.4.22.27
• FLJ50259
• MGC3886

Background

Cathepsin S is a lysosomal cysteine protease of the papain family. Human Cathepsin S is synthesized as a preproenzyme of 331 amino acid residues consisting a signal peptide (residues 1 - 16), a pro region (residues 17 - 114), and the mature enzyme (residues 115 - 331).

Publications for Cathepsin S (DY1183)(12)

Publications using DY1183

• Zisman, D;Sabtan, H;Rahat, MM;Simanovich, E;Haddad, A;Gazitt, T;Feld, J;Slobodin, G;Kibari, A;Elias, M;Rahat, MA; Tofacitinib Regulates Endostatin via Effects on CD147 and Cathepsin S International journal of molecular sciences 2024-07-02 [PMID: 39000375] (Human)
• Alehagen, U;Alexander, J;Aaseth, JO;Larsson, A;Svensson, E;Opstad, TB; Effects of an Intervention with Selenium and Coenzyme Q10 on Five Selected Age-Related Biomarkers in Elderly Swedes Low in Selenium: Results That Point to an Anti-Ageing Effect-A Sub-Analysis of a Previous Prospective Double-Blind Placebo-Controlled Randomised Clinical Trial Cells 2023-07-04 [PMID: 37443807] (Human)
• M Liu, AN Panagopoul, UM Oguz, S Samant, CH Vasa, DK Agrawal, YS Chatzizisi Role of triggering receptor expressed on myeloid cells-1 in the mechanotransduction signaling pathways that link low shear stress with inflammation Scientific Reports, 2023-03-21;13(1):4656. 2023-03-21 [PMID: 36944850] (Human)
• M Liu, S Samant, CH Vasa, RM Pedrigi, UM Oguz, S Ryu, T Wei, DR Anderson, DK Agrawal, YS Chatzizisi Co-culture models of endothelial cells, macrophages, and vascular smooth muscle cells for the study of the natural history of atherosclerosis PLoS ONE, 2023-01-20;18(1):e0280385. 2023-01-20 [PMID: 36662769] (Human)
• I Govorov, K Bremme, A Larsson, M Holmström, E Komlichenk, R Chaireti, M Mints Blood inflammatory and endothelial markers in women with von Willebrand disease PLoS ONE, 2019-01-10;14(1):e0210544. 2019-01-10 [PMID: 30629692] (Human)
• E Fernlund, T Gyllenhamm, R Jablonowsk, M Carlsson, A Larsson, J Ärnlöv, P Liuba Serum Biomarkers of Myocardial Remodeling and Coronary Dysfunction in Early Stages of Hypertrophic Cardiomyopathy in the Young Pediatr Cardiol, 2017-03-30;0(0):. 2017-03-30 [PMID: 28361263] (Human)
• D Steubl, SV Kumar, M Tato, SR Mulay, A Larsson, L Lind, U Risérus, L Renders, U Heemann, AC Carlsson, J Ärnlöv, HJ Anders Circulating cathepsin-S levels correlate with GFR decline and sTNFR1 and sTNFR2 levels in mice and humans Sci Rep, 2017-02-27;7(0):43538. 2017-02-27 [PMID: 28240259] (Human)
• Plasma Cathepsin S and Cathepsin S/Cystatin C Ratios Are Potential Biomarkers for COPD Dis. Markers, 2016-11-22;2016(0):4093870. 2016-11-22 [PMID: 27994288] (Human)
• Evaluating the diagnostic and prognostic value of circulating cathepsin S in gastric cancer Oncotarget, 2016-05-10;7(19):28124-38. 2016-05-10 [PMID: 27058412] (Human)
• Alam M, Getz M, Yi S, Kurkewich J, Safeukui I, Haldar K Plasma signature of neurological disease in the monogenetic disorder Niemann-Pick Type C. J Biol Chem, 2014-01-31;289(12):8051-66. 2014-01-31 [PMID: 24488491] (Mouse)
• Lv B, Lindholt J, Cheng X, Wang J, Shi G Plasma cathepsin S and cystatin C levels and risk of abdominal aortic aneurysm: a randomized population-based study. PLoS ONE, 2012-07-23;7(7):e41813. 2012-07-23 [PMID: 22844527] (Human)
• Jobs E, Riserus U, Ingelsson E, Helmersson J, Nerpin E, Jobs M, Sundstrom J, Lind L, Larsson A, Basu S, Arnlov J Serum cathepsin S is associated with serum C-reactive protein and interleukin-6 independently of obesity in elderly men. J. Clin. Endocrinol. Metab., 2010-07-07;95(9):4460-4. 2010-07-07 [PMID: 20610597] (Human)

FAQs for Cathepsin S (DY1183). (Showing 1 - 1 of 1 FAQs).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.

Bioinformatics

• Gene Symbol: CTSS