TIMP-1 Products

Antibodies
TIMP-1 Antibody [Unconjugated ...
TIMP-1 Antibody [Unconjugated]
Species: Hu
Applications: WB, Simple Western, IHC, B/N, KO
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  
TIMP-1 Antibody [Unconjugated ...
TIMP-1 Antibody [Unconjugated]
AF980
Species: Mu
Applications: WB, IHC, IP, B/N
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  
Antibody Pairs
TIMP-1 Antibody Pair [HRP]
TIMP-1 Antibody Pair [HRP]
NBP2-79290
Species: Hu
Applications: S-ELISA
Conjugate Catalog # Availability Size Price
ELISA Kits
Human TIMP-1 Quantikine ELISA ...
Human TIMP-1 Quantikine ELISA Kit
DTM100
Species: Hu
Applications: ELISA
Conjugate Catalog # Availability Size Price
Human TIMP-1 DuoSet ELISA, 15 ...
Human TIMP-1 DuoSet ELISA, 15 Plate
DY970
Species: Hu
Applications: ELISA
Conjugate Catalog # Availability Size Price
Mouse TIMP-1 Quantikine ELISA ...
Mouse TIMP-1 Quantikine ELISA Kit
MTM100
Species: Mu
Applications: ELISA
Lysates
TIMP-1 Overexpression Lysate
TIMP-1 Overexpression Lysate
NBL1-16924
Species: Hu
Applications: WB
Proteins
Recombinant Human TIMP-1 Prot ...
Recombinant Human TIMP-1 Protein, CF
970-TM
Species: Hu
Applications: Inhibition Activity
Formulation Catalog # Availability Price  
Recombinant Mouse TIMP-1 Prot ...
Recombinant Mouse TIMP-1 Protein, CF
980-MT
Species: Mu
Applications: Inhibition Activity
Formulation Catalog # Availability Price  
Recombinant Rat TIMP-1 Protei ...
Recombinant Rat TIMP-1 Protein, CF
580-RT
Species: Rt
Applications: Inhibition Activity
Formulation Catalog # Availability Price  

Description

Tissue inhibitor of metalloproteinases 1 (TIMP1) and Tissue inhibitor of metalloproteinases 2 (TIMP 2) have similar properties, specifically in inhibiting enzymes of matrix metalloproteinase family, and are thought to be of great importance in the maintenance of connective tissue integrity. TIMP1 forms a complex of 1:1 stoichiometry with activated interstitial collagenases, activated stromelysin, active form of 72kDa Type IV collagenase (also known as MMP2 or gelatinase A), and latent and active forms 92kDa Type IV collagenase (also known as MMP0 or gelatinase B). TIMPs inhibit the proteolytic invasiveness of tumour cells and normal placental trophoblast cells. TIMP1 is produced in low (pg/ml) levels by most cell types. Treatment of cells with the phorbol ester TPA stimulates production of TIMP1 in some cell types, but the low protein levels produced often require concentration of cell culture media to visualize the bands by Western Blotting.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Mouse
Product By Gene ID 7076
Alternate Names
  • metalloproteinase inhibitor 1
  • Tissue inhibitor of metalloproteinases 1
  • erythroid potentiating activity
  • Fibroblast collagenase inhibitor
  • Erythroid-potentiating activity
  • HCI
  • Collagenase inhibitor
  • FLJ90373
  • EPO
  • collagenase inhibitor)
  • TIMPtissue inhibitor of metalloproteinase 1 (erythroid potentiating activity
  • EPATIMP-1
  • CLGI
  • TIMP metallopeptidase inhibitor 1

Research Areas for TIMP-1

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Cancer
Cell Biology
Cell Cycle and Replication
Cellular Markers
Cytoskeleton Markers
Extracellular Matrix

Bioinformatics Tool for TIMP-1

Discover related pathways, diseases and genes to TIMP-1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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