TIMP-1 Products

Antibodies
TIMP-1 Antibody (63515) [Unco ...
TIMP-1 Antibody (63515) [Unconjuga...
MAB970
Species: Hu
Applications: WB, IHC, CyTOF-ready, ELISA(Cap), ICFlow
Host: Mouse Monoclonal
TIMP-1 Antibody [Unconjugated ...
TIMP-1 Antibody [Unconjugated]
AF980
Species: Mu
Applications: WB, IHC, IP, Neut
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
TIMP-1 Antibody [Unconjugated ...
TIMP-1 Antibody [Unconjugated]
AF970
Species: Hu
Applications: WB, Neut
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Antibody Pairs
TIMP-1 Antibody Pair
TIMP-1 Antibody Pair
H00007076-PW1
Species: Hu
Applications: WB, IP
TIMP-1 Antibody Pair
TIMP-1 Antibody Pair
H00007076-AP41
Species: Hu
Applications: S-ELISA
ELISA Kits
TIMP-1 ELISA Kit [Biotin]
TIMP-1 ELISA Kit [Biotin]
KA0437
Species: Rt
TIMP-1 ELISA Kit
TIMP-1 ELISA Kit
NBP1-82424
Species: Hu
Applications: ELISA
TIMP-1 ELISA Kit [Biotin]
TIMP-1 ELISA Kit [Biotin]
KA1815
Species: Mu
Lysates
TIMP-1 Overexpression Lysate ...
TIMP-1 Overexpression Lysate (Native)
NBL1-16924
Applications: WB
TIMP-1 Overexpression Lysate ...
TIMP-1 Overexpression Lysate (Dena...
H00007076-T02
Species: Hu
Applications: WB
Proteins
TIMP-1 Recombinant Protein An ...
TIMP-1 Recombinant Protein Antigen
NBP2-38700PEP
Species: Hu
Applications: AC
Recombinant Mouse TIMP-1 Prot ...
Recombinant Mouse TIMP-1 Protein
NBP2-52187
Species: Mu
Applications: PAGE
Recombinant Rat TIMP-1 Protei ...
Recombinant Rat TIMP-1 Protein
NBP2-52180
Species: Rt
Applications: PAGE
RNAi
TIMP-1 RNAi
TIMP-1 RNAi
H00007076-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Tissue inhibitor of metalloproteinases 1 (TIMP1) and Tissue inhibitor of metalloproteinases 2 (TIMP 2) have similar properties, specifically in inhibiting enzymes of matrix metalloproteinase family, and are thought to be of great importance in the maintenance of connective tissue integrity. TIMP1 forms a complex of 1:1 stoichiometry with activated interstitial collagenases, activated stromelysin, active form of 72kDa Type IV collagenase (also known as MMP2 or gelatinase A), and latent and active forms 92kDa Type IV collagenase (also known as MMP0 or gelatinase B). TIMPs inhibit the proteolytic invasiveness of tumour cells and normal placental trophoblast cells. TIMP1 is produced in low (pg/ml) levels by most cell types. Treatment of cells with the phorbol ester TPA stimulates production of TIMP1 in some cell types, but the low protein levels produced often require concentration of cell culture media to visualize the bands by Western Blotting.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Mouse
Product By Gene ID 7076
Alternate Names
  • metalloproteinase inhibitor 1
  • Tissue inhibitor of metalloproteinases 1
  • erythroid potentiating activity
  • Fibroblast collagenase inhibitor
  • Erythroid-potentiating activity
  • HCI
  • Collagenase inhibitor
  • FLJ90373
  • EPO
  • collagenase inhibitor)
  • TIMPtissue inhibitor of metalloproteinase 1 (erythroid potentiating activity
  • EPATIMP-1
  • CLGI
  • TIMP metallopeptidase inhibitor 1

Research Areas for TIMP-1

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Cancer
Cell Biology
Cell Cycle and Replication
Cellular Markers
Cytoskeleton Markers
Extracellular Matrix

Bioinformatics Tool for TIMP-1

Discover related pathways, diseases and genes to TIMP-1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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