TIMP-1 Antibody [Unconjugated] Summary
Mouse myeloma cell line NS0-derived recombinant human TIMP-1
Accession # Q6FGX5
Detects human TIMP-1 in direct ELISAs and Western blots. In direct ELISAs, approximately 20% cross-reactivity with recombinant mouse TIMP‑1 and recombinant rat TIMP-1 is observed and less than 1% cross-reactivity with recombinant human (rh) TIMP-2, rhTIMP-3, and rhTIMP‑4 is observed.
<0.10 EU per 1 μg of the antibody by the LAL method.
Test in a species/application not listed above to receive a full credit towards a future purchase.
- Western Blot 1-5 ug/mL
- Simple Western 50 ug/mL
- Immunohistochemistry 1-15 ug/mL
- Knockout Validated
- Neutralization 1 ug/mL
Packaging, Storage & Formulations
|Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Reconstitute at 0.2 mg/mL in sterile PBS.
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for TIMP-1 Antibody [Unconjugated]
- Collagenase inhibitor
- collagenase inhibitor)
- erythroid potentiating activity
- Erythroid-potentiating activity
- Fibroblast collagenase inhibitor
- metalloproteinase inhibitor 1
- TIMP metallopeptidase inhibitor 1
- TIMPtissue inhibitor of metalloproteinase 1 (erythroid potentiating activity
- Tissue inhibitor of metalloproteinases 1
Tissue inhibitors of metalloproteinases or TIMPs are a family of proteins that regulate the activation and proteolytic activity of the zinc enzymes known as matrix metalloproteinases (MMPs). There are four members of the family, TIMP-1, TIMP-2, TIMP-3 and TIMP-4. TIMP-1 is a glycoprotein with a molecular mass of 28 kDa produced by a wide range of cell types. TIMP-1 inhibits active MMP-mediated proteolysis by forming an N-terminal, non-covalent binary complex with the MMP active site. TIMP-1 also associates C-terminally with Pro-MMP-9 in a complex which may play a role in regulating activation. Independent of MMPs, TIMP-1 has been shown to have a role in tissue homeostasis.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
Customers Who Viewed This Item Also Viewed...
Species: Hu, Mu, Rt, Po, Ca
Species: Hu, Mu, Rt
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP
Applications: WB, Simple Western, IHC, B/N, KO
Product General Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
FAQs for TIMP-1 Antibody (AF970) (0)
Other Available Formats
Additional TIMP-1 Products
Bioinformatics Tool for TIMP-1 Antibody (AF970)
Discover related pathways, diseases and genes to TIMP-1 Antibody (AF970). Need help?
Read the Bioinformatics Tool Guide
for instructions on using this tool.
Blogs on TIMP-1