Human sTNF RII/TNFRSF1B DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human sTNF RII/TNFRSF1B DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: TNFRSF1B

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human sTNF RII/TNFRSF1B DuoSet ELISA, 15 Plate

• CD120b antigen
• CD120b
• Etanercept
• p75 TNF receptor
• p75TBPII
• p75TNFR
• soluble TNFR1B variant 1
• TNF RII
• TNFBRp80 TNF-alpha receptor
• TNF-R2
• TNFR2TNFR1B
• TNF-R75
• TNFR80
• TNFRII
• TNF-RII
• TNF-R-II
• TNFR-II
• TNFRSF1B
• tumor necrosis factor beta receptor
• tumor necrosis factor binding protein 2
• Tumor necrosis factor receptor 2
• tumor necrosis factor receptor superfamily member 1B
• tumor necrosis factor receptor superfamily, member 1B
• Tumor necrosis factor receptor type II

Background

TNF RII (Tumor Necrosis Factor Receptor II), also known as TNFRSF1B, p75/p80, and CD120b, is a widely expressed receptor for membrane-associated TNF-alpha and Lymphotoxin-alpha. Its activation initiates pro-inflammatory and pro-survival responses via NFkB-dependent signaling pathways, although it may also induce apoptosis.

Publications for TNF RII/TNFRSF1B (DY726)(31)

Publications using DY726

• da Costa Teixeira, LA;Soares, LA;Lima, LP;Avelar, NCP;de Moura, JA;Leopoldino, AAO;Figueiredo, PHS;Parentoni, AN;Mendonça, VA;Lacerda, ACR; Cognitive function is associated with performance in time up and go test and with leptin blood levels in community-dwelling older women Scientific reports 2024-04-29 [PMID: 38684691] (Human)
• Augusto da Costa Teixeira, L;Rocha-Vieira, E;Aparecida Soares, L;Mota de Oliveira, F;Aparecida Oliveira Leopoldino, A;Netto Parentoni, A;Amaral Mendonça, V;Cristina Rodrigues Lacerda, A; The strong inverse association between plasma concentrations of soluble tumor necrosis factor receptors type 1 with adiponectin/leptin ratio in older women Cytokine 2024-01-27 [PMID: 38281360] (Human)
• Viegas, ÂA;Santos, T;Nobre, JNP;Santos, JMD;Silva Lage, VKD;Fernandes, AC;Peixoto, MFD;Morais, RLS;Sartorio, A;Mendonça, VA;Lacerda, ACR; Association between biomarkers of redox status and cytokines with different patterns of habitual physical activity in eutrophic and overweight/obese preschoolers: multivariate analysis of a cross-sectional study BMC public health 2023-11-28 [PMID: 38017390] (Human)
• Arthanarisami, A;Komaru, Y;Katsouridi, C;Schumacher, J;Verges, DK;Ning, L;Abdelmageed, MM;Herrlich, A;Kefaloyianni, E; Acute Kidney Injury-Induced Circulating TNFR1/2 Elevations Correlate with Persistent Kidney Injury and Progression to Fibrosis Cells 2023-09-05 [PMID: 37759437] (Human)
• da Costa Teixeira, LA;Avelar, NCP;Peixoto, MFD;Parentoni, AN;Santos, JMD;Pereira, FSM;Danielewicz, AL;Leopoldino, AAO;Costa, SP;Arrieiro, AN;Soares, LA;da Silva Lage, VK;Prates, ACN;Taiar, R;de Carvalho Bastone, A;Oliveira, VC;Oliveira, MX;Costa, HS;Nobre, JNP;Brant, FP;Duarte, TC;Figueiredo, PHS;Mendonça, VA;Lacerda, ACR; Inflammatory biomarkers at different stages of Sarcopenia in older women Scientific reports 2023-06-26 [PMID: 37365209] (Human)
• LAC Teixeira, JM Dos Santos, AN Parentoni, LP Lima, TC Duarte, FP Brant, CDC Neves, FSM Pereira, NCP Avelar, AL Danielewic, AAO Leopoldino, SP Costa, AN Arrieiro, LA Soares, ACN Prates, JNP Nobre, A de Carvalh, VC de Oliveir, MX Oliveira, PH Scheidt Fi, HS Costa, V Amaral Men, R Taiar, AC Rodrigues Adiponectin Is a Contributing Factor of Low Appendicular Lean Mass in Older Community-Dwelling Women: A Cross-Sectional Study Journal of Clinical Medicine, 2022-12-02;11(23):. 2022-12-02 [PMID: 36498747] (Human)
• T Baram, N Oren, N Erlichman, T Meshel, A Ben-Baruch Inflammation-Driven Regulation of PD-L1 and PD-L2, and Their Cross-Interactions with Protective Soluble TNFalpha Receptors in Human Triple-Negative Breast Cancer Cancers, 2022-07-19;14(14):. 2022-07-19 [PMID: 35884574] (Human)
• S Hong, KH Park, YE Lee, JE Lee, YM Kim, E Joo, I Cho Antibody microarray analysis of amniotic fluid proteomes in women with cervical insufficiency and short cervix, and their association with pregnancy latency length PLoS ONE, 2022-02-07;17(2):e0263586. 2022-02-07 [PMID: 35130326] (Human)
• ICS Dias, SM de Campos-, ELM Vieira, APL Mota, PS Azevedo, VTDS Anício, FC Guimarães, LM Mantovani, BF Cruz, AL Teixeira, JV Salgado Adiponectin and Stnfr2 peripheral levels are associated with cardiovascular risk in patients with schizophrenia Journal of psychiatric research, 2021-11-09;0(0):. 2021-11-09 [PMID: 34785039] (Human)
• E Sancho Fer, K Hanslin, M Hultström, A Larsson, R Frithiof, M Lipcsey, Uppsala In Soluble TNF receptors predict acute kidney injury and mortality in critically ill COVID-19 patients: A prospective observational study Cytokine, 2021-10-05;149(0):155727. 2021-10-05 [PMID: 34628127] (Human)
• AM Weckman, AL Conroy, M Madanitsa, B Gnaneswara, CR McDonald, L Kalilani-P, J Chandna, D Ali, V Mwapasa, C Khairallah, KL Thwai, SR Meshnick, SM Taylor, FO Ter Kuile, KC Kain, M Gladstone Neurocognitive outcomes in Malawian children exposed to malaria during pregnancy: An observational birth cohort study PLoS medicine, 2021-09-28;18(9):e1003701. 2021-09-28 [PMID: 34582452] (Human)
• Y Palacios, A Ruiz, LA Ramón-Luin, R Ocaña-Guzm, O Barreto-Ro, A Sánchez-Mo, B Tecuatzi-C, AG Regalado-G, RD Pineda-Gud, A García-Mar, F Juárez-Her, JP Farias-Con, I Fricke-Gal, G Pérez-Rubi, R Falfán-Val, I Buendia-Ro, K Medina-Que, L Chavez-Gal Severe COVID-19 Patients Show an Increase in Soluble TNFR1 and ADAM17, with a Relationship to Mortality International Journal of Molecular Sciences, 2021-08-05;22(16):. 2021-08-05 [PMID: 34445140] (Human)
• CDC Neves, VKS Lage, LP Lima, MA Matos, ÉLM Vieira, AL Teixeira, PHS Figueiredo, HS Costa, ACR Lacerda, VA Mendonça Inflammatory and oxidative biomarkers as determinants of functional capacity in patients with COPD assessed by 6-min walk test-derived outcomes Experimental gerontology, 2021-06-21;152(0):111456. 2021-06-21 [PMID: 34166733] (Human)
• S Novelli, C Lécuroux, C Goujard, J Reynes, A Villemant, L Blum, A Essat, V Avettand-F, O Launay, JM Molina, C Bourgeois, L Meyer Persistence of monocyte activation under treatment in people followed since acute HIV-1 infection relative to participants at high or low risk of HIV infection EBioMedicine, 2020-11-26;62(0):103129. 2020-11-26 [PMID: 33248370] (Human)
• M Bergquist, L Samuelsson, A Larsson, J Tydén, J Johansson, M Lipcsey TNFR1, TNFR2, neutrophil gelatinase-associated lipocalin and heparin binding protein in identifying sepsis and predicting outcome in an intensive care cohort Scientific Reports, 2020-09-18;10(1):15350. 2020-09-18 [PMID: 32948801] (Human)
• CR McDonald, AM Weckman, AL Conroy, P Olwoch, P Natureeba, MR Kamya, DV Havlir, G Dorsey, KC Kain Systemic inflammation is associated with malaria and preterm birth in women living with HIV on antiretrovirals and co-trimoxazole Sci Rep, 2019-05-01;9(1):6758. 2019-05-01 [PMID: 31043691] (Human)
• IG Barbosa, RA Ferreira, NP Rocha, GC Mol, F da Mata Ch, IE Bauer, AL Teixeira Predictors of cognitive performance in bipolar disorder: The role of educational degree and inflammatory markers J Psychiatr Res, 2018-09-17;106(0):31-37. 2018-09-17 [PMID: 30261412] (Human)
• PHS Figueiredo, MMO Lima, HS Costa, JB Martins, OD Flecha, PF Gonçalves, FL Alves, VGB Rodrigues, EHB Maciel, VA Mendonça, ACR Lacerda, ÉLM Vieira, AL Teixeira, F de Paula, CH Balthazar Effects of the inspiratory muscle training and aerobic training on respiratory and functional parameters, inflammatory biomarkers, redox status and quality of life in hemodialysis patients: A randomized clinical trial PLoS ONE, 2018-07-26;13(7):e0200727. 2018-07-26 [PMID: 30048473] (Human)
• J Panezai, A Ghaffar, M Altamash, PE Engström, A Larsson Periodontal disease influences osteoclastogenic bone markers in subjects with and without rheumatoid arthritis PLoS ONE, 2018-06-11;13(6):e0197235. 2018-06-11 [PMID: 29889832] (Human)
• Neuroendocrine Inflammatory Responses in Overweight/Obese Infants PLoS ONE, 2016-12-01;11(12):e0167593. 2016-12-01 [PMID: 27907172] (Human)
• CC Mok, HH Ding, M Kharboutli, C Mohan Axl, Ferritin, Insulin-Like Growth Factor Binding Protein 2, and Tumor Necrosis Factor Receptor Type II as Biomarkers in Systemic Lupus Erythematosus Arthritis Care Res (Hoboken), 2016-07-28;68(9):1303-9. 2016-07-28 [PMID: 26749069] (Human)
• McDonald C, Darling A, Conroy A, Tran V, Cabrera A, Liles W, Wang M, Aboud S, Urassa W, Fawzi W, Kain K Inflammatory and Angiogenic Factors at Mid-Pregnancy Are Associated with Spontaneous Preterm Birth in a Cohort of Tanzanian Women. PLoS ONE, 2015-08-06;10(8):e0134619. 2015-08-06 [PMID: 26247200] (Human)
• Carlsson A, Larsson T, Helmersson-Karlqvist J, Larsson A, Lind L, Arnlov J Soluble TNF receptors and kidney dysfunction in the elderly. J Am Soc Nephrol, 2014-02-07;25(6):1313-20. 2014-02-07 [PMID: 24511129] (Human)
• Neuenschwander LC, Bittencourt H, Ribeiro AF, Teixeira AL, Teixeira MM, Teixeira JC, Nobre V Plasma levels of procalcitonin and eight additional inflammatory molecules in febrile neutropenic patients. Clinics (Sao Paulo), 2011-01-01;66(10):1699-705. 2011-01-01 [PMID: 22012040] (Human)
• Li X, Magenheimer BS, Xia S, Johnson T, Wallace DP, Calvet JP, Li R A tumor necrosis factor-alpha-mediated pathway promoting autosomal dominant polycystic kidney disease. Nat. Med., 2008-06-15;14(8):863-8. 2008-06-15 [PMID: 18552856] (Human)
• Hsu HY, Wittemann S, Schneider EM, Weiss M, Joos TO Suspension microarrays for the identification of the response patterns in hyperinflammatory diseases. Med Eng Phys, 2008-03-03;30(8):976-83. 2008-03-03 [PMID: 18313970] (Human)
• van Mierlo GJ, Scherer HU, Hameetman M, Morgan ME, Flierman R, Huizinga TW, Toes RE Cutting edge: TNFR-shedding by CD4+CD25+ regulatory T cells inhibits the induction of inflammatory mediators. J. Immunol., 2008-03-01;180(5):2747-51. 2008-03-01 [PMID: 18292492] (Human)
• Mattey DL, Glossop JR, Nixon NB, Dawes PT Circulating levels of tumor necrosis factor receptors are highly predictive of mortality in patients with rheumatoid arthritis. Arthritis Rheum., 2007-12-01;56(12):3940-8. 2007-12-01 [PMID: 18050238] (Human)
• Glossop JR, Dawes PT, Nixon NB, Mattey DL Polymorphism in the tumour necrosis factor receptor II gene is associated with circulating levels of soluble tumour necrosis factor receptors in rheumatoid arthritis. Arthritis Res. Ther., 2005-09-07;7(6):R1227-34. 2005-09-07 [PMID: 16277675] (Human)
• Chan BP, Yuen WF, Lee WH, Wong SN, Chung TY, Wu YJ, Pang SF Immunomodulating effects of CKBM on the cytokine production in peripheral blood mononuclear cells (PBMCs) from healthy volunteers. Immunopharmacol Immunotoxicol, 2004-05-01;26(2):177-92. 2004-05-01 [PMID: 15209354] (Human)
• Petit-Bertron AF, Fitting C, Cavaillon JM, Adib-Conquy M Adherence influences monocyte responsiveness to interleukin-10. J. Leukoc. Biol., 2003-01-01;73(1):145-54. 2003-01-01 [PMID: 12525572] (Human)

FAQs for TNF RII/TNFRSF1B (DY726). (Showing 1 - 1 of 1 FAQs).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.

Bioinformatics

• Gene Symbol: TNFRSF1B